Background Patients with critical illness can lose more than 15% of muscle mass in one
week, and this can have long-term detrimental effects. However, there is currently no …

Preserving muscle is not only crucial for maintaining proper physical movement, but also for
its many metabolic and homeostatic roles. Low muscle mass has been shown to adversely …

After acute infection with the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-
2), many individuals experience a range of symptoms including dyspnea, exercise …

Background: Intensive care patients commonly develop muscle wasting and functional
impairment. However, the role of severe COVID-19 in the magnitude of muscle wasting and …

Purpose Muscle wasting is common amongst patients with persistent critical illness and
associated with increased urea production, but reduced creatinine production. We …

Rationale: Dietary protein may attenuate the muscle atrophy experienced by patients in the
ICU, yet protein handling is poorly understood. Objectives: To quantify protein digestion and …

Intensive care unit-acquired weakness (ICUAW) occurs in critically ill patients stemming from
the critical illness itself, and results in sustained disability long after the ICU stay. Weakness …

Background Acute skeletal muscle wasting in critical illness is associated with excess
morbidity and mortality. Continuous feeding may suppress muscle protein synthesis as a …

Intensive care unit–acquired weakness (ICU-AW) is the most common neuromuscular
impairment in critically ill patients. We discuss critical aspects of ICU-AW that have not been …

Mitochondrial biology has seen a surge in popularity in the past 5 years, with the emergence
of numerous new avenues of exciting mitochondria-related research including …