Catechol-O-Methyltransferase (COMT): An Update on Its Role in Cancer, Neurological and Cardiovascular Diseases
Abstract Catechol-O-methyltransferase (COMT) is an enzyme that catalyses the methylation
of catechol substrates, classically in catecholamine metabolism, but also acting upon other …
of catechol substrates, classically in catecholamine metabolism, but also acting upon other …
Central nervous system plasticity influences language and cognitive recovery in adult glioma
Gliomas exist within the framework of complex neuronal circuitry in which network dynamics
influence both tumor biology and cognition. The generalized impairment of cognition or loss …
influence both tumor biology and cognition. The generalized impairment of cognition or loss …
Hypothesizing music intervention enhances brain functional connectivity involving dopaminergic recruitment: common neuro-correlates to abusable drugs
K Blum, T Simpatico, M Febo, C Rodriquez… - Molecular …, 2017 - Springer
The goal of this review is to explore the clinical significance of music listening on
neuroplasticity and dopaminergic activation by understanding the role of music therapy in …
neuroplasticity and dopaminergic activation by understanding the role of music therapy in …
Age-specific associations among functional COMT Val158Met polymorphism, resting parasympathetic nervous control and generalized anxiety disorder
Abstract The functional Val 158 Met polymorphism (rs4680) of the Catechol-O-
Methyltransferase (COMT) gene has been implicated in generalized anxiety disorder (GAD); …
Methyltransferase (COMT) gene has been implicated in generalized anxiety disorder (GAD); …
Associations of the COMT Val158Met polymorphism with working memory and intelligence–A review and meta-analysis
Abstract The Val 158 Met polymorphism influences the activity of the Catechol-O-Methyl-
Transferase (COMT), an enzyme involved in dopamine metabolism. Dopamine availability is …
Transferase (COMT), an enzyme involved in dopamine metabolism. Dopamine availability is …
COMT and the neurogenetic architecture of hearing loss induced tinnitus
S Vanneste, O Alsalman, D De Ridder - Hearing Research, 2018 - Elsevier
As the COMT polymorphism is especially prominent in the prefrontal cortex and has been
associated with auditory gating, we hypothesize that tinnitus patients with this polymorphism …
associated with auditory gating, we hypothesize that tinnitus patients with this polymorphism …
Effects of COMT rs4680 and BDNF rs6265 polymorphisms on brain degree centrality in Han Chinese adults who lost their only child
Losing one's only child is a major traumatic life event that may lead to posttraumatic stress
disorder (PTSD); however, not all parents who experience this trauma develop PTSD …
disorder (PTSD); however, not all parents who experience this trauma develop PTSD …
The influence of COMT rs4680 on functional connectivity in healthy adults: A systematic review
KA Morris, SA Grace, W Woods, B Dean… - European Journal of …, 2020 - Wiley Online Library
The aim of this systematic review was to qualitatively synthesise the available research that
investigated the influence of COMT genotype at SNP rs4680 on both task‐based and resting …
investigated the influence of COMT genotype at SNP rs4680 on both task‐based and resting …
The multiverse of data preprocessing and analysis in graph-based fMRI: A systematic literature review of analytical choices fed into a decision support tool for …
The large number of different analytical choices researchers use may be partly responsible
for the replication challenge in neuroimaging studies. For robustness analysis, knowledge of …
for the replication challenge in neuroimaging studies. For robustness analysis, knowledge of …
The role of the COMT val158met polymorphism in mediating aversive learning in visual cortex
The catechol-O-methyltransferase (COMT) val158met single nucleotide polymorphism
(SNP) alters metabolic activity of the COMT enzyme regulating catecholamines, with the Val …
(SNP) alters metabolic activity of the COMT enzyme regulating catecholamines, with the Val …