Extracellular miRNAs: from biomarkers to mediators of physiology and disease

MA Mori, RG Ludwig, R Garcia-Martin, BB Brandão… - Cell metabolism, 2019 - cell.com
miRNAs can be found in serum and other body fluids and serve as biomarkers for disease.
More importantly, secreted miRNAs, especially those in extracellular vesicles (EVs) such as …

Circulating extracellular vesicles in human disease

R Shah, T Patel, JE Freedman - New England Journal of …, 2018 - Mass Medical Soc
Circulating Extracellular Vesicles in Human Disease | New England Journal of Medicine Skip to
main content The New England Journal of Medicine homepage Advanced Search SEARCH …

Extracellular vesicles and their emerging roles as cellular messengers in endocrinology: an endocrine society scientific statement

C Salomon, S Das, U Erdbrügger, R Kalluri… - Endocrine …, 2022 - academic.oup.com
During the last decade, there has been great interest in elucidating the biological role of
extracellular vesicles (EVs), particularly, their hormone-like role in cell-to-cell …

Extracellular vesicles: novel mediators of cell communication in metabolic disease

I Huang-Doran, CY Zhang, A Vidal-Puig - Trends in Endocrinology & …, 2017 - cell.com
Metabolic homeostasis emerges from the complex, multidirectional crosstalk between key
metabolic tissues including adipose tissue, liver, and skeletal muscle. This crosstalk …

Extracellular vesicles in renal disease

D Karpman, A Ståhl, I Arvidsson - Nature Reviews Nephrology, 2017 - nature.com
Extracellular vesicles, such as exosomes and microvesicles, are host cell-derived packages
of information that allow cell–cell communication and enable cells to rid themselves of …

Obesity may accelerate the aging process

V Salvestrini, C Sell, A Lorenzini - Frontiers in endocrinology, 2019 - frontiersin.org
Lines of evidence from several studies have shown that increases in life expectancy are now
accompanied by increased disability rate. The expanded lifespan of the aging population …

Microvesicles and exosomes: new players in metabolic and cardiovascular disease

C Lawson, JM Vicencio, DM Yellon… - Journal of …, 2016 - joe.bioscientifica.com
The past decade has witnessed an exponential increase in the number of publications
referring to extracellular vesicles (EVs). For many years considered to be extracellular …

Extracellular vesicles in metabolic disease

N Akbar, V Azzimato, RP Choudhury, M Aouadi - Diabetologia, 2019 - Springer
Extracellular vesicles (EVs) are submicron-sized lipid envelopes that are produced and
released from a parent cell and can be taken up by a recipient cell. EVs are capable of …

Microvesicles in vascular homeostasis and diseases

VC Ridger, CM Boulanger… - Thrombosis and …, 2017 - thieme-connect.com
Microvesicles are members of the family of extracellular vesicles shed from the plasma
membrane of activated or apoptotic cells. Microvesicles were initially characterised by their …

Extracellular vesicles in obesity and diabetes mellitus

F Pardo, R Villalobos-Labra, B Sobrevia… - Molecular aspects of …, 2018 - Elsevier
Cell-to-cell communication happens via diverse mechanisms including the synthesis,
release and transfer to target cells of extracellular vesicles (EVs). EVs include nanovesicles …