Resveratrol: A double-edged sword in health benefits

B Salehi, AP Mishra, M Nigam, B Sener, M Kilic… - Biomedicines, 2018 - mdpi.com
Resveratrol (3, 5, 4′-trihydroxy-trans-stilbene) belongs to polyphenols' stilbenoids group,
possessing two phenol rings linked to each other by an ethylene bridge. This natural …

Resveratrol and endothelial function: A literature review

N Parsamanesh, A Asghari, S Sardari… - Pharmacological …, 2021 - Elsevier
Endothelial dysfunction is a major contributing factor to diseases such as atherosclerosis,
diabetes mellitus, obesity, hypertension, acute lung injury, preeclampsia, among others …

Anti-inflammatory effects of resveratrol: Mechanistic insights

D de Sá Coutinho, MT Pacheco, RL Frozza… - International journal of …, 2018 - mdpi.com
Inflammation is the principal response invoked by the body to address injuries. Despite
inflammation constituting a crucial component of tissue repair, it is well known that …

Resveratrol-selenium nanoparticles alleviate neuroinflammation and neurotoxicity in a rat model of Alzheimer's disease by regulating Sirt1/miRNA-134/GSK3β …

OAR Abozaid, MW Sallam, S El-Sonbaty… - … Trace Element Research, 2022 - Springer
Alzheimer's disease (AD) is a brain disorder associated with a gradual weakening in
neurocognitive functions, neuroinflammation, and impaired signaling pathways. Resveratrol …

Therapeutic effects and safe uses of plant-derived polyphenolic compounds in cardiovascular diseases: a review

BS Alotaibi, M Ijaz, M Buabeid, ZJ Kharaba… - Drug design …, 2021 - Taylor & Francis
Polyphenols have long been recognized as health-promoting entities, including beneficial
effects on cardiovascular disease, but their reputation has been boosted recently following a …

A review of resveratrol as a potent chemoprotective and synergistic agent in cancer chemotherapy

Q Xiao, W Zhu, W Feng, SS Lee, AW Leung… - Frontiers in …, 2019 - frontiersin.org
Background: Cancer has become a major disease endangering human health around the
world. Conventional chemotherapy suffers from many side effects including pain …

The effect of resveratrol on the cardiovascular system from molecular mechanisms to clinical results

R Gal, L Deres, K Toth, R Halmosi, T Habon - International journal of …, 2021 - mdpi.com
Cardiovascular diseases are the leading causes of death worldwide. The cardioprotective
effects of natural polyphenols such as resveratrol (3, 5, 4-trihydroxystilbene) have been …

Effects of doxorubicin on the heart: From molecular mechanisms to intervention strategies

N Prathumsap, K Shinlapawittayatorn… - European journal of …, 2020 - Elsevier
Cancer remains a major public health problem worldwide and was responsible for 9.6
million deaths in 2018. Oncologic treatments such as doxorubicin (Dox) and trastuzumab …

Inhibition of NF-κB signaling pathway by resveratrol improves spinal cord injury

L Xu, BOA Botchway, S Zhang, J Zhou… - Frontiers in …, 2018 - frontiersin.org
Spinal cord injury (SCI) can have a significant impact on an individual's life. Herein, we
discuss how resveratrol improves SCI by inhibiting nuclear factor kappa-light-chain …

Resveratrol in cancer patients: from bench to bedside

M Berretta, A Bignucolo, R Di Francia… - International journal of …, 2020 - mdpi.com
Resveratrol (3, 5, 4′-trihydroxystilbene) is a natural phytoalexin that accumulates in several
vegetables and fruits like nuts, grapes, apples, red fruits, black olives, capers, red rice as …