Furin‐mediated protein processing in infectious diseases and cancer
E Braun, D Sauter - Clinical & translational immunology, 2019 - Wiley Online Library
Proteolytic cleavage regulates numerous processes in health and disease. One key player
is the ubiquitously expressed serine protease furin, which cleaves a plethora of proteins at …
is the ubiquitously expressed serine protease furin, which cleaves a plethora of proteins at …
Ebola haemorrhagic fever
H Feldmann, TW Geisbert - The Lancet, 2011 - thelancet.com
Ebola viruses are the causative agents of a severe form of viral haemorrhagic fever in man,
designated Ebola haemorrhagic fever, and are endemic in regions of central Africa. The …
designated Ebola haemorrhagic fever, and are endemic in regions of central Africa. The …
Genomic surveillance elucidates Ebola virus origin and transmission during the 2014 outbreak
SK Gire, A Goba, KG Andersen, RSG Sealfon, DJ Park… - science, 2014 - science.org
In its largest outbreak, Ebola virus disease is spreading through Guinea, Liberia, Sierra
Leone, and Nigeria. We sequenced 99 Ebola virus genomes from 78 patients in Sierra …
Leone, and Nigeria. We sequenced 99 Ebola virus genomes from 78 patients in Sierra …
[HTML][HTML] Systematic analysis of monoclonal antibodies against Ebola virus GP defines features that contribute to protection
Antibodies are promising post-exposure therapies against emerging viruses, but which
antibody features and in vitro assays best forecast protection are unclear. Our international …
antibody features and in vitro assays best forecast protection are unclear. Our international …
Discovery of an ebolavirus-like filovirus in europe
A Negredo, G Palacios, S Vázquez-Morón… - PLoS …, 2011 - journals.plos.org
Filoviruses, amongst the most lethal of primate pathogens, have only been reported as
natural infections in sub-Saharan Africa and the Philippines. Infections of bats with the …
natural infections in sub-Saharan Africa and the Philippines. Infections of bats with the …
An overlapping essential gene in the Potyviridae
The family Potyviridae includes> 30% of known plant virus species, many of which are of
great agricultural significance. These viruses have a positive sense RNA genome that is≈ …
great agricultural significance. These viruses have a positive sense RNA genome that is≈ …
Proposal for a revised taxonomy of the family Filoviridae: classification, names of taxa and viruses, and virus abbreviations
The taxonomy of the family Filoviridae (marburgviruses and ebolaviruses) has changed
several times since the discovery of its members, resulting in a plethora of species and virus …
several times since the discovery of its members, resulting in a plethora of species and virus …
Therapeutic strategies to target the Ebola virus life cycle
Following the Ebola virus disease epidemic in west Africa, there has been increased
awareness of the need for improved therapies for emerging diseases, including viral …
awareness of the need for improved therapies for emerging diseases, including viral …
Comparison of the transcription and replication strategies of Marburg virus and Ebola virus by using artificial replication systems
E Mühlberger, M Weik, VE Volchkov… - Journal of …, 1999 - Am Soc Microbiol
The members of the family Filoviridae, Marburg virus (MBGV) and Ebola virus (EBOV), are
very similar in terms of morphology, genome organization, and protein composition. To …
very similar in terms of morphology, genome organization, and protein composition. To …
Rapid diagnosis of Ebola hemorrhagic fever by reverse transcription-PCR in an outbreak setting and assessment of patient viral load as a predictor of outcome
The largest outbreak on record of Ebola hemorrhagic fever (EHF) occurred in Uganda from
August 2000 to January 2001. The outbreak was centered in the Gulu district of northern …
August 2000 to January 2001. The outbreak was centered in the Gulu district of northern …