[HTML][HTML] Selective autophagy: ATG8 family proteins, LIR motifs and cargo receptors
T Johansen, T Lamark - Journal of molecular biology, 2020 - Elsevier
Selective autophagy relies on soluble or membrane-bound cargo receptors that recognize
cargo and bring about autophagosome formation at the cargo. The cargo-bound receptors …
cargo and bring about autophagosome formation at the cargo. The cargo-bound receptors …
The ATG conjugation systems in autophagy
N Mizushima - Current opinion in cell biology, 2020 - Elsevier
Autophagosome formation and maturation involve the two ubiquitin-like systems: The ATG8
and ATG12 systems. ATG8 (LC3s and gamma-aminobutyric acid receptor–associated …
and ATG12 systems. ATG8 (LC3s and gamma-aminobutyric acid receptor–associated …
Regulation of selective autophagy: the p62/SQSTM1 paradigm
T Lamark, S Svenning, T Johansen - Essays in biochemistry, 2017 - portlandpress.com
In selective autophagy, cytoplasmic components are selected and tagged before being
sequestered into an autophagosome by means of selective autophagy receptors such as …
sequestered into an autophagosome by means of selective autophagy receptors such as …
Roles of autophagy in oxidative stress
HR Yun, YH Jo, J Kim, Y Shin, SS Kim… - International journal of …, 2020 - mdpi.com
Autophagy is a catabolic process for unnecessary or dysfunctional cytoplasmic contents by
lysosomal degradation pathways. Autophagy is implicated in various biological processes …
lysosomal degradation pathways. Autophagy is implicated in various biological processes …
Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1
DJ Klionsky, AK Abdel-Aziz, S Abdelfatah, M Abdellatif… - autophagy, 2021 - Taylor & Francis
In 2008, we published the first set of guidelines for standardizing research in autophagy.
Since then, this topic has received increasing attention, and many scientists have entered …
Since then, this topic has received increasing attention, and many scientists have entered …
Starvation induces rapid degradation of selective autophagy receptors by endosomal microautophagy
J Mejlvang, H Olsvik, S Svenning, JA Bruun… - Journal of cell …, 2018 - rupress.org
It is not clear to what extent starvation-induced autophagy affects the proteome on a global
scale and whether it is selective. In this study, we report based on quantitative proteomics …
scale and whether it is selective. In this study, we report based on quantitative proteomics …
Digesting the expanding mechanisms of autophagy
NT Ktistakis, SA Tooze - Trends in cell biology, 2016 - cell.com
Autophagy is a catabolic 'self-eating'pathway that is emerging as a crucial integration point
in cell physiology. With its own set of genes, the autophagy pathway communicates with …
in cell physiology. With its own set of genes, the autophagy pathway communicates with …
Activation and targeting of ATG8 protein lipidation
S Martens, D Fracchiolla - Cell discovery, 2020 - nature.com
ATG8 family proteins are evolutionary conserved ubiquitin-like modifiers, which become
attached to the headgroup of the membrane lipid phosphatidylethanolamine in a process …
attached to the headgroup of the membrane lipid phosphatidylethanolamine in a process …
The regulation of autophagy by calcium signals: Do we have a consensus?
Abstract Macroautophagy (hereafter called 'autophagy') is a cellular process for degrading
and recycling cellular constituents, and for maintenance of cell function. Autophagy initiates …
and recycling cellular constituents, and for maintenance of cell function. Autophagy initiates …
[HTML][HTML] Mammalian hybrid pre-autophagosomal structure HyPAS generates autophagosomes
The biogenesis of mammalian autophagosomes remains to be fully defined. Here, we used
cellular and in vitro membrane fusion analyses to show that autophagosomes are formed …
cellular and in vitro membrane fusion analyses to show that autophagosomes are formed …