Mediators of the resolution of the inflammatory response
The termination of inflammation is governed by endogenous molecules collectively referred
to as 'mediators of resolution'of inflammation. There is now strong evidence to suggest that …
to as 'mediators of resolution'of inflammation. There is now strong evidence to suggest that …
Bone fragility during the COVID-19 pandemic: the role of macro-and micronutrients
Bone fragility is the susceptibility to fracture due to poor bone strength. This condition is
usually associated with aging, comorbidities, disability, poor quality of life, and increased …
usually associated with aging, comorbidities, disability, poor quality of life, and increased …
The angiotensin converting enzyme 2/angiotensin-(1-7)/Mas Receptor axis as a key player in alveolar bone remodeling
CM Queiroz-Junior, ACPM Santos, I Galvão, GR Souto… - Bone, 2019 - Elsevier
The renin-angiotensin system (RAS), aside its classical hormonal properties, has been
implicated in the pathogenesis of inflammatory disorders. The angiotensin converting …
implicated in the pathogenesis of inflammatory disorders. The angiotensin converting …
Xanthenone, ACE2 activator, counteracted gentamicin-induced nephrotoxicity in rats: impact on oxidative stress and ACE2/Ang-(1–7) signaling
Nephrotoxicity is a rapid deterioration of kidney function due to exposure to nephrotoxic
drugs as gentamicin. Gentamicin increases the generation of reactive oxygen species (ROS) …
drugs as gentamicin. Gentamicin increases the generation of reactive oxygen species (ROS) …
Angiotensin-(1-7) promotes resolution of neutrophilic inflammation in a model of antigen-induced arthritis in mice
LC Barroso, GS Magalhaes, I Galvão, AC Reis… - Frontiers in …, 2017 - frontiersin.org
Defective resolution of inflammation may be crucial for the initiation and development of
chronic inflammatory diseases, such as arthritis. Therefore, it has been suggested that …
chronic inflammatory diseases, such as arthritis. Therefore, it has been suggested that …
GLP-1 mediates regulation of colonic ACE2 expression by the bile acid receptor GPBAR1 in inflammation
Background & Aims: ACE2, a carboxypeptidase that generates Ang-(1-7) from Ang II, is
highly expressed in the lung, small intestine and colon. GPBAR1, is a G protein bile acid …
highly expressed in the lung, small intestine and colon. GPBAR1, is a G protein bile acid …
Modulation of brain ACE and ACE2 may be a promising protective strategy against cerebral ischemia/reperfusion injury: an experimental trial in rats
MM Abdel-Fattah, BAS Messiha… - … Schmiedeberg's archives of …, 2018 - Springer
The brain renin-angiotensin system (RAS) is considered a crucial regulator for physiological
homeostasis and disease progression. We evaluated the protective effects of the …
homeostasis and disease progression. We evaluated the protective effects of the …
What do we know about the renin angiotensin system and inflammatory bowel disease?
SW Lo, JP Segal, JS Lubel, M Garg - Expert Opinion on …, 2022 - Taylor & Francis
Introduction The renin-angiotensin system (RAS) is an important homeostatic pathway, with
emerging evidence for the impact of its components on inflammation and fibrosis in …
emerging evidence for the impact of its components on inflammation and fibrosis in …
Onion bulb extract reduces colitis severity in mice via modulation of colonic inflammatory pathways and the apoptotic machinery
Ethnopharmacological relevance The use of nutraceutical-based products has increased in
recent years due to their demonstrated efficacy and their good safety profile. Onion is one of …
recent years due to their demonstrated efficacy and their good safety profile. Onion is one of …
Azelaic Acid Regulates the Renin–Angiotensin System and Improves Colitis Based on Network Pharmacology and Experimentation
Y Liao, X Wu, W Luo, J Chen, Y Huang, K Ma… - ACS …, 2023 - ACS Publications
Inflammatory bowel disease (IBD), which encompasses Crohn's disease and ulcerative
colitis, has a complicated etiology that might be brought on by metabolic dysbiosis. Previous …
colitis, has a complicated etiology that might be brought on by metabolic dysbiosis. Previous …