Objective: To review the use of airway pressure release ventilation (APRV) in the treatment
of acute lung injury/acute respiratory distress syndrome. Data Source: Published animal …

The extensive pulmonary alveolar and capillary networks make the lungs highly susceptible
to cell and tissue injury from pathogens or toxic environmental agents present either in the …

Objective: The open lung approach is a mechanical ventilation strategy involving lung
recruitment and a decremental positive end-expiratory pressure trial. We compared the …

Rationale: The hypothesis that lung collapse is detrimental during the acute respiratory
distress syndrome is still debatable. One of the difficulties is the lack of an efficient maneuver …

Background A lung-protective ventilatory strategy with low tidal volume (VT) has been
proposed for use in acute respiratory distress syndrome (ARDS). Alveolar derecruitment …

Objective Positive end-expiratory pressure (PEEP) and recruitment maneuvers (RMs) may
partially reverse atelectasis and reduce ventilation-associated lung injury. The purposes of …

The objective was to analyze the physiologic effects of recruitment maneuvers (RM) in 17
patients with acute respiratory distress syndrome (ARDS) ventilated with a lung protective …

Approximately 16% of deaths in patients with ARDS results from refractory hypoxemia,
which is the inability to achieve adequate arterial oxygenation despite high levels of inspired …

Objective To assess how the level of positive end-expiratory pressure (PEEP)(
antiderecruitment strategy), etiological category of diffuse lung injury, and body position of …

Acute lung injury (ALI) and the acute respiratory distress syndrome (ARDS) are
characterized by rapid-onset respiratory failure following a variety of direct and indirect …