Bacterial biofilm and its role in the pathogenesis of disease

LK Vestby, T Grønseth, R Simm, LL Nesse - Antibiotics, 2020 - mdpi.com
Recognition of the fact that bacterial biofilm may play a role in the pathogenesis of disease
has led to an increased focus on identifying diseases that may be biofilm-related. Biofilm …

The in vivo biofilm

T Bjarnsholt, M Alhede, M Alhede… - Trends in …, 2013 - cell.com
Bacteria can grow and proliferate either as single, independent cells or organized in
aggregates commonly referred to as biofilms. When bacteria succeed in forming a biofilm …

[HTML][HTML] ESCMID guideline for the diagnosis and treatment of biofilm infections 2014

N Høiby, T Bjarnsholt, C Moser, GL Bassi… - Clinical microbiology …, 2015 - Elsevier
Biofilms cause chronic infections in tissues or by developing on the surfaces of medical
devices. Biofilm infections persist despite both antibiotic therapy and the innate and adaptive …

The role of bacterial biofilms in chronic infections

T Bjarnsholt - Apmis, 2013 - Wiley Online Library
Acute infections caused by pathogenic bacteria have been studied extensively for well over
100 years. These infections killed millions of people in previous centuries, but they have …

Towards diagnostic guidelines for biofilm-associated infections

L Hall-Stoodley, P Stoodley, S Kathju… - FEMS Immunology & …, 2012 - academic.oup.com
Biofilms associated with the human body, particularly in typically sterile locations, are difficult
to diagnose and treat effectively because of their recalcitrance to conventional antibiotic …

Biofilm aggregates and the host airway-microbial interface

L Hall-Stoodley, KS McCoy - Frontiers in Cellular and Infection …, 2022 - frontiersin.org
Biofilms are multicellular microbial aggregates that can be associated with host mucosal
epithelia in the airway, gut, and genitourinary tract. The host environment plays a critical role …

The pathogens profile in children with otitis media with effusion and adenoid hypertrophy

GP Buzatto, E Tamashiro, JL Proenca-Modena… - PLoS …, 2017 - journals.plos.org
Objectives To evaluate the presence of viruses and bacteria in middle ear and adenoids of
patients with and without otitis media with effusion (OME). Methods Adenoid samples and …

Non-Typeable Haemophilus influenzae Invasion and Persistence in the Human Respiratory Tract

CF Clementi, TF Murphy - Frontiers in cellular and infection …, 2011 - frontiersin.org
Non-typeable Haemophilus influenzae (NTHI) is an opportunistic bacterial pathogen of the
human respiratory tract and is a leading cause of respiratory infections in children and …

Role of adenoid biofilm in chronic otitis media with effusion in children

ME Saafan, WS Ibrahim, MO Tomoum - European Archives of Oto-Rhino …, 2013 - Springer
To study the extent of surface adenoid biofilm and to evaluate its role in the pathogenesis of
chronic otitis media with effusion (COME) in children. The study was carried out on 100 …

Noninvasive depth‐resolved optical measurements of the tympanic membrane and middle ear for differentiating otitis media

GL Monroy, RL Shelton, RM Nolan… - The …, 2015 - Wiley Online Library
Objective/Hypothesis In this study, optical coherence tomography (OCT) is used to
noninvasively and quantitatively determine tympanic membrane (TM) thickness and the …