Poor water solubility of many drugs has emerged as one of the major challenges in the
pharmaceutical world. Polymer-based amorphous solid dispersions have been considered …

Dissolution rate of a poorly water-soluble drug, fenofibrate, is increased by adsorbing the
drug onto silica. The adsorption is achieved by first dissolving the drug in supercritical …

Amorphous nifedipine− PVP and phenobarbital− PVP solid dispersions with various drug
contents were prepared by melting and subsequent rapid cooling of mixtures of PVP and …

Tadalafil is an efficient drug used to treat erectile dysfunction characterized by poor water
solubility, which has a negative influence on its bioavailability. Utilization of microporous …

Aceclofenac is a potent anti-inflammatory analgesic agent indicated for acute and chronic
treatment of rheumatoid arthritis, ostio arthritis, onkylosing spondylytis. Aceclofenac is poorly …

INTRODUCTION Over the past two decades, advances in drug discovery techniques have
been significant in identifying new and novel therapeutics agents in the pharmaceutical …

The purpose of this study was to improve the melt extrusion processability of polyvinyl
acetate phthalate (PVAP) and investigate its use as a stabilizing polymer for supersaturated …

Due to the increased use of nanocomposites, nanocatalysts, and nano-pharmaceuticals,
mixing at nanoscale has become important. Conventional mixing techniques can be …