Biological therapies in immune-mediated inflammatory diseases: can biosimilars reduce access inequities?

DC Baumgart, L Misery, S Naeyaert… - Frontiers in …, 2019 - frontiersin.org
Biological therapies are an effective treatment for a range of immune-mediated inflammatory
diseases (IMIDs), including rheumatoid arthritis, psoriasis, and inflammatory bowel …

The future of biosimilars: maximizing benefits across immune-mediated inflammatory diseases

HU Kim, R Alten, L Avedano, A Dignass, F Gomollón… - Drugs, 2020 - Springer
Biologics have transformed the treatment of immune-mediated inflammatory diseases such
as rheumatoid arthritis (RA) and inflammatory bowel disease (IBD). Biosimilars—biologic …

Safety, immunogenicity and interchangeability of biosimilar monoclonal antibodies and fusion proteins: a regulatory perspective

P Kurki, S Barry, I Bourges, P Tsantili, E Wolff-Holz - Drugs, 2021 - Springer
Background Biosimilars have been used for 15 years in the European Union (EU), and have
been shown to reduce costs and increase access to important biological medicines. In spite …

Era of biosimilars in rheumatology: reshaping the healthcare environment

JS Smolen, J Goncalves, M Quinn, F Benedetti… - RMD open, 2019 - rmdopen.bmj.com
Compared with the original approved biological drug on which it is based, a biosimilar has
highly similar physicochemical characteristics and biological activity, as well as equivalent …

Biosimilar-to-biosimilar switching: what is the rationale and current experience?

E Mysler, VF Azevedo, S Danese, D Alvarez, N Iikuni… - Drugs, 2021 - Springer
Over time, clinicians have become increasingly comfortable embracing the prescription of
biosimilars—highly similar versions of innovator or reference biological agents—for their …

Switching between reference adalimumab and biosimilars in chronic immune‐mediated inflammatory diseases: A systematic literature review

N García‐Beloso, I Altabás‐González… - British Journal of …, 2022 - Wiley Online Library
Aims Adalimumab is a biological therapy used to treat different chronic inflammatory
diseases. At present, there is an increasing number of adalimumab biosimilars. To assume …

Switching to biosimilar SDZ-ADL in patients with moderate-to-severe active rheumatoid arthritis: 48-week efficacy, safety and immunogenicity results from the phase III …

P Wiland, S Jeka, E Dokoupilová, J Brandt-Jürgens… - BioDrugs, 2020 - Springer
Abstract Background Sandoz adalimumab SDZ-ADL (GP-2017) is an approved adalimumab
biosimilar with similar efficacy and comparable safety and immunogenicity to reference …

Budget impact of switching to biosimilar trastuzumab (CT-P6) for the treatment of breast cancer and gastric cancer in 28 European countries

SM Lee, JH Jung, D Suh, YS Jung, SL Yoo, DW Kim… - BioDrugs, 2019 - Springer
Background As the economic burden of treating cancer patients has been soaring in
European countries, performing a budget impact analysis is becoming one of the …

Knowledge, attitude, and practice towards biosimilars and interchangeable products: a prescriptive insight by the pharmacists

S Shakeel, MA Hassali, H Rehman… - … journal of general …, 2020 - Taylor & Francis
Background Pharmacists being the drug experts need to be well aware of the applied
handling of biosimilar medicines (BSMs). They are an integral educator, trailblazer, and …

Use of follow-on disease-modifying treatments for multiple sclerosis: Consensus recommendations

WJ Brownlee, C Wolf, HP Hartung… - Multiple Sclerosis …, 2022 - journals.sagepub.com
Background: As patents for multiple sclerosis (MS) therapies expire, follow-on disease-
modifying treatments (FO-DMTs) become available at reduced cost. Concerns exist that …