[HTML][HTML] Syndecans in inflammation at a glance
S Gopal - Frontiers in immunology, 2020 - frontiersin.org
Syndecans are transmembrane proteoglycans with heparan and chondroitin sulfate chains
attached to their extracellular domain. Like many proteoglycans, they interact with a large …
attached to their extracellular domain. Like many proteoglycans, they interact with a large …
NSAIDs: learning new tricks from old drugs
F Díaz‐González… - European journal of …, 2015 - Wiley Online Library
Nonsteroidal anti‐inflammatory drugs (NSAIDs) comprise a heterogeneous group of
pharmacological agents used for the symptomatic treatment of fever, pain, and inflammation …
pharmacological agents used for the symptomatic treatment of fever, pain, and inflammation …
Complement modulates the cutaneous microbiome and inflammatory milieu
The skin is colonized by a plethora of microbes that include commensals and potential
pathogens, but it is currently unknown how cutaneous host immune mechanisms influence …
pathogens, but it is currently unknown how cutaneous host immune mechanisms influence …
Structural ECM components in the premetastatic and metastatic niche
AM Høye, JT Erler - American Journal of Physiology-Cell …, 2016 - journals.physiology.org
The aim of this review is to give an overview of the extracellular matrix (ECM) components
that are important for creating structural changes in the premetastatic and metastatic niche …
that are important for creating structural changes in the premetastatic and metastatic niche …
[HTML][HTML] IL-33 promotes CD11b/CD18-mediated adhesion of eosinophils to cancer cells and synapse-polarized degranulation leading to tumor cell killing
S Andreone, F Spadaro, C Buccione, J Mancini… - Cancers, 2019 - mdpi.com
Eosinophils are major effectors of Th2-related pathologies, frequently found infiltrating
several human cancers. We recently showed that eosinophils play an essential role in anti …
several human cancers. We recently showed that eosinophils play an essential role in anti …
[HTML][HTML] Therapeutic targets in allergic conjunctivitis
BA Labib, DGI Chigbu - Pharmaceuticals, 2022 - mdpi.com
Allergic conjunctivitis (AC) is a common condition resulting from exposure to allergens such
as pollen, animal dander, or mold. It is typically mediated by allergen-induced crosslinking of …
as pollen, animal dander, or mold. It is typically mediated by allergen-induced crosslinking of …
[HTML][HTML] LFA-1 (CD11a/CD18) and Mac-1 (CD11b/CD18) distinctly regulate neutrophil extravasation through hotspots I and II
YM Hyun, YH Choe, SA Park, M Kim - Experimental & molecular …, 2019 - nature.com
Precise spatiotemporal regulation of leukocyte extravasation is key for generating an
efficient immune response to injury or infection. The integrins LFA-1 (CD11a/CD18) and Mac …
efficient immune response to injury or infection. The integrins LFA-1 (CD11a/CD18) and Mac …
The involvement of a chemokine receptor antagonist CTCE‐9908 and kynurenine metabolites in cancer development
DS Nkandeu, C Basson, AM Joubert… - Cell Biochemistry …, 2022 - Wiley Online Library
Cancer is the second leading cause of mortality worldwide. Skin cancer is the most common
cancer in South Africa with nearly 20,000 reported cases every year and 700 deaths. If …
cancer in South Africa with nearly 20,000 reported cases every year and 700 deaths. If …
[HTML][HTML] Endothelial dysfunction in the context of blood–brain barrier modeling
AG Kutikhin, DK Shishkova, EA Velikanova… - Journal of Evolutionary …, 2022 - Springer
Here, we discuss pathophysiological approaches to the defining of endothelial dysfunction
criteria (ie, endothelial activation, impaired endothelial mechanotransduction, endothelial-to …
criteria (ie, endothelial activation, impaired endothelial mechanotransduction, endothelial-to …
[HTML][HTML] CSK-mediated signalling by integrins in cancer
H Maldonado, L Leyton - Frontiers in Cell and Developmental Biology, 2023 - frontiersin.org
Cancer progression and metastasis are processes heavily controlled by the integrin receptor
family. Integrins are cell adhesion molecules that constitute the central components of …
family. Integrins are cell adhesion molecules that constitute the central components of …