Strategies for Improving Transdermal Administration: New Approaches to Controlled Drug Release

O Dumitriu Buzia, AM Păduraru, CS Stefan, M Dinu… - Pharmaceutics, 2023 - mdpi.com
In this work, we aim to address several strategies to improve transdermal drug delivery, such
as iontophoresis, sonophoresis, electroporation and micron. We also propose a review of …

[HTML][HTML] Strategies for Improving Transdermal Administration: New Approaches to Controlled Drug Release

OD Buzia, AM Păduraru, CS Stefan, M Dinu… - …, 2023 - ncbi.nlm.nih.gov
In this work, we aim to address several strategies to improve transdermal drug delivery, such
as iontophoresis, sonophoresis, electroporation and micron. We also propose a review of …

Ionic liquid-based formulation approaches for enhanced transmucosal drug delivery

O Khan, R Bhawale, R Vasave, NK Mehra - Drug Discovery Today, 2024 - Elsevier
Highlights•ILs, a potential approach for improving physico-chemical and biological
properties of APIs.•Mucus membranes serves as a barrier for drug delivery.•Choline-based …

Mechanisms of Biological Effects of Ionic Liquids: From Single Cells to Multicellular Organisms

KS Egorova, AV Kibardin, AV Posvyatenko… - Chemical …, 2024 - ACS Publications
The review presents a detailed discussion of the evolving field studying interactions
between ionic liquids (ILs) and biological systems. Originating from molten salt electrolytes …

Advances of ionic liquid-based nanohybrids for biomedical applications

LY Li, YR Gao, R Xue, Y Shu, JH Wang… - Journal of Materials …, 2023 - pubs.rsc.org
Ionic liquids (ILs) are composed of asymmetric cationic and anionic moieties and are used
as green solvents. Their non-toxic nature, favorable biocompatibility and adjustable structure …

[PDF][PDF] Permeation enhancement and advanced strategies: a comprehensive review of improved topical drug delivery

BA Patel - International Research Journal of Modernization in …, 2024 - researchgate.net
Transdermal drug delivery offers a promising alternative to conventional routes, with benefits
like painless administration and avoidance of first-pass metabolism. However, the skin's …

Development of Cholinium-Based API Ionic Liquids with Enhanced Drug Solubility: Biological Evaluation and Interfacial Properties

AR Bhat, RA Padder, M Husain… - Molecular Pharmaceutics, 2024 - ACS Publications
We report an efficient sustainable two-step anion exchange synthetic procedure for the
preparation of choline API ionic liquids (Cho-API-ILs) that contain active pharmaceutical …

Effects of imidazolium ionic liquids on skin barrier lipids–Perspectives for drug delivery

G Paraskevopoulos, F Fandrei, AK Pratihast… - Journal of Colloid and …, 2024 - Elsevier
Ionic liquids (ILs) have great potential to facilitate transdermal and topical drug delivery.
Here, we investigated the mechanism of action of amphiphilic ILs 1-methyl-3 …

Hyaluronic acid-protein conjugate modified iron-based MOFs (MIL-101 (Fe)) for efficient therapy of neuroblastoma: Molecular simulation, stability and toxicity studies

AN Nikam, A Pandey, SH Nannuri, G Fernandes… - Crystals, 2022 - mdpi.com
Iron-based metal-organic frameworks (MIL (101)) have recently gained attention in materials
science for biomedical applications. In the present work, Iron-based MOF (MIL-101 (Fe)) …

[HTML][HTML] Cations of amino acid alkyl esters conjugated with an anion from the group of NSAIDs–As tunable pharmaceutical active ionic liquids

J Klebeko, P Ossowicz-Rupniewska, A Nowak… - Journal of Molecular …, 2023 - Elsevier
Herein, we investigated the effect of pairing the L-amino acid alkyl (propyl, isopropyl, or
butyl) ester on the formation of API-ILs. The novel salts of NSAIDs (non-steroidal anti …