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Primary hyperoxaluria type I (PH1) is an autosomal recessive disease caused by the
functional defect of alanine-glyoxylate aminotransferase that results in the overproduction of …

Primary hyperoxaluria Type 1 is a rare autosomal recessive inborn error of glyoxylate
metabolism, caused by a deficiency of the liver-specific enzyme alanine: glyoxylate …

Primary hyperoxalurias (PH) are inborn errors in the metabolism of glyoxylate and oxalate.
PH type 1, the most common form, is an autosomal recessive disorder caused by a …

Oxalate arthropathy is a rare cause of arthritis characterized by deposition of calcium oxalate
crystals within synovial fluid. This condition typically occurs in patients with underlying …

Growth retardation, decreased final height and renal osteodystrophy (ROD) are common
complications of childhood chronic kidney disease (CKD), resulting from a combination of …

Mineral and bone disorder (MBD) is widely prevalent in children with chronic kidney disease
(CKD) and is associated with significant morbidity. CKD may cause disturbances in bone …

Background Infants with chronic kidney disease (CKD) form a vulnerable population who
are highly prone to mineral and bone disorders (MBD) including biochemical abnormalities …

Dialysis patients have compromised bone health that increases their fracture risk due to low
bone mass and deterioration in bone microarchitecture. Through meta-analyses of …

Deposition of calcium oxalate crystals in the kidney and bone is a hallmark of primary
hyperoxaluria (PH). Since the bone compartment can store massive amounts of oxalate …