Bacteriophages inhibit and evade cGAS-like immune function in bacteria
E Huiting, X Cao, J Ren, JS Athukoralage, Z Luo… - Cell, 2023 - cell.com
A fundamental strategy of eukaryotic antiviral immunity involves the cGAS enzyme, which
synthesizes 2′, 3′-cGAMP and activates the effector STING. Diverse bacteria contain …
synthesizes 2′, 3′-cGAMP and activates the effector STING. Diverse bacteria contain …
Bacteriophages of Pseudomonas
PJ Ceyssens, R Lavigne - Future microbiology, 2010 - Taylor & Francis
Pseudomonas species and their bacteriophages have been studied intensely since the
beginning of the 20th century, due to their ubiquitous nature, and medical and ecological …
beginning of the 20th century, due to their ubiquitous nature, and medical and ecological …
Antagonistic coevolution of marine planktonic viruses and their hosts
The potential for antagonistic coevolution between marine viruses and their (primarily
bacterial) hosts is well documented, but our understanding of the consequences of this rapid …
bacterial) hosts is well documented, but our understanding of the consequences of this rapid …
[HTML][HTML] Antagonistic coevolution accelerates molecular evolution
Abstract The Red Queen hypothesis proposes that coevolution of interacting species (such
as hosts and parasites) should drive molecular evolution through continual natural selection …
as hosts and parasites) should drive molecular evolution through continual natural selection …
Quality-controlled small-scale production of a well-defined bacteriophage cocktail for use in human clinical trials
We describe the small-scale, laboratory-based, production and quality control of a cocktail,
consisting of exclusively lytic bacteriophages, designed for the treatment of Pseudomonas …
consisting of exclusively lytic bacteriophages, designed for the treatment of Pseudomonas …
Host–parasite coevolutionary arms races give way to fluctuating selection
Ecology Letters (2011) 14: 635–642 Abstract Host–parasite coevolution is a key driver of
biological diversity and parasite virulence, but its effects depend on the nature of …
biological diversity and parasite virulence, but its effects depend on the nature of …
[HTML][HTML] Unifying classical and molecular taxonomic classification: analysis of the Podoviridae using BLASTP-based tools
We defined phage genera by measuring genome relationships by the numbers of shared
homologous/orthologous proteins. We used BLAST-based tools (CoreExtractor. vbs and …
homologous/orthologous proteins. We used BLAST-based tools (CoreExtractor. vbs and …
Isolation and in vitro evaluation of bacteriophages against MDR-bacterial isolates from septic wound infections
Multi-drug resistance has become a major problem for the treatment of pathogenic bacterial
infections. The use of bacteriophages is an attractive approach to overcome the problem of …
infections. The use of bacteriophages is an attractive approach to overcome the problem of …
Antibacterial activity of Acinetobacter baumannii phage ϕAB2 endolysin (LysAB2) against both Gram-positive and Gram-negative bacteria
MJ Lai, NT Lin, A Hu, PC Soo, LK Chen… - Applied microbiology …, 2011 - Springer
To investigate the nature and origin of the antibacterial activity of the lytic phage ϕAB2
toward Acinetobacter baumannii, we successfully isolated and characterized a novel phage …
toward Acinetobacter baumannii, we successfully isolated and characterized a novel phage …
Reticulate representation of evolutionary and functional relationships between phage genomes
G Lima-Mendez, J Van Helden… - Molecular biology …, 2008 - academic.oup.com
Bacteriophage genomes show pervasive mosaicism, indicating the importance of horizontal
gene exchange in their evolution. Phage genomes represent unique combinations of …
gene exchange in their evolution. Phage genomes represent unique combinations of …