Fibroblast growth factors (FGFs) are a family of heparin-binding growth factors. FGFs exert
their pro-angiogenic activity by interacting with various endothelial cell surface receptors …

Angiogenesis inhibitors are a new class of drugs, for which the general rules involving
conventional chemotherapy might not apply. The successful translation of angiogenesis …

We tested the hypothesis that intravenous infusion of human bone marrow stromal cells
(hMSCs) promotes vascular endothelial growth factor (VEGF) secretion, VEGF receptor 2 …

Biological processes that drive cell growth are exciting targets for cancer therapy. The
fibroblast growth factor (FGF) signaling network plays a ubiquitous role in normal cell …

Fibroblast growth factor (FGF) signaling regulates cell proliferation, differentiation, survival,
angiogenesis, and wound healing. Compelling evidence for deregulated FGF signaling in …

Life originated in anoxia, but many organisms came to depend upon oxygen for survival,
independently evolving diverse respiratory systems for acquiring oxygen from the …

Bone is highly vascularized tissue reliant on coordinated coupling between angiogenesis
and osteogenesis to regenerate. Delivery of a combination of growth factors involved in the …

Abstract Neuropilin 2 (NRP2) is a receptor for the vascular endothelial growth factor (VEGF)
and the semaphorin (SEMA) families, 2 unrelated ligand families involved in angiogenesis …

Rationale: Effective neovascularization is crucial for recovery after cardiovascular events.
Objective: Because microRNAs regulate expression of up to several hundred target genes …

Numerous studies have suggested a link between the angiogenic FGF and VEGF signaling
pathways; however, the nature of this link has not been established. To evaluate this …