[HTML][HTML] The evolution of neurofilament light chain in multiple sclerosis
C Ferreira-Atuesta, S Reyes, G Giovanonni… - Frontiers in …, 2021 - frontiersin.org
Multiple sclerosis (MS) is an autoimmune, inflammatory neurodegenerative disease of the
central nervous system characterized by demyelination and axonal damage. Diagnosis and …
central nervous system characterized by demyelination and axonal damage. Diagnosis and …
Body fluid biomarkers in multiple sclerosis
M Comabella, X Montalban - The Lancet Neurology, 2014 - thelancet.com
Biomarkers can be thought of as multifaceted indicators of healthy status or of pathological
disorders. The study of multiple sclerosis can benefit from the use of biomarkers because of …
disorders. The study of multiple sclerosis can benefit from the use of biomarkers because of …
Neurofilaments as biomarkers in multiple sclerosis
CE Teunissen, M Khalil - Multiple sclerosis journal, 2012 - journals.sagepub.com
Neurodegeneration is the correlate of disease progression in multiple sclerosis (MS) and
thus biological biomarkers that sensitively reflect this process are much needed …
thus biological biomarkers that sensitively reflect this process are much needed …
[HTML][HTML] B cells are multifunctional players in multiple sclerosis pathogenesis: insights from therapeutic interventions
N Claes, J Fraussen, P Stinissen, R Hupperts… - Frontiers in …, 2015 - frontiersin.org
Multiple sclerosis (MS) is a severe disease of the central nervous system (CNS)
characterized by autoimmune inflammation and neurodegeneration. Historically, damage to …
characterized by autoimmune inflammation and neurodegeneration. Historically, damage to …
A defect of sphingolipid metabolism modifies the properties of normal appearing white matter in multiple sclerosis
Maintaining the appropriate complement and content of lipids in cellular membranes is
critical for normal neural function. Accumulating evidence suggests that even subtle …
critical for normal neural function. Accumulating evidence suggests that even subtle …
Disease biomarkers in multiple sclerosis: potential for use in therapeutic decision making
VK Harris, SA Sadiq - Molecular diagnosis & therapy, 2009 - Springer
Multiple sclerosis (MS) is an autoimmune disorder of the brain and spinal cord that
predominantly affects white matter. MS has a variable clinical presentation and has no …
predominantly affects white matter. MS has a variable clinical presentation and has no …
Disease origin and progression in amyotrophic lateral sclerosis: an immunology perspective
A Malaspina, F Puentes, S Amor - International immunology, 2015 - academic.oup.com
The immune system is inextricably linked with many neurodegenerative diseases including
amyotrophic lateral sclerosis (ALS), a devastating neuromuscular disorder affecting motor …
amyotrophic lateral sclerosis (ALS), a devastating neuromuscular disorder affecting motor …
Brain antigens in functionally distinct antigen-presenting cell populations in cervical lymph nodes in MS and EAE
M van Zwam, R Huizinga, MJ Melief… - Journal of molecular …, 2009 - Springer
Drainage of central nervous system (CNS) antigens to the brain-draining cervical lymph
nodes (CLN) is likely crucial in the initiation and control of autoimmune responses during …
nodes (CLN) is likely crucial in the initiation and control of autoimmune responses during …
Biomarkers of therapeutic response in multiple sclerosis: current status
VK Harris, SA Sadiq - Molecular diagnosis & therapy, 2014 - Springer
Multiple sclerosis (MS) is an autoimmune disease of unknown cause, in which chronic
inflammation drives multifocal demyelination of axons in both white and gray matter in the …
inflammation drives multifocal demyelination of axons in both white and gray matter in the …
Targets of the humoral autoimmune response in multiple sclerosis
J Fraussen, N Claes, L de Bock, V Somers - Autoimmunity reviews, 2014 - Elsevier
Multiple sclerosis (MS) is an inflammatory disorder of the central nervous system (CNS) with
heterogeneous clinical, genetic and pathophysiological characteristics. The establishment of …
heterogeneous clinical, genetic and pathophysiological characteristics. The establishment of …