Metal‐Based Nanozymes with Multienzyme‐Like Activities as Therapeutic Candidates: Applications, Mechanisms, and Optimization Strategy

D Li, D Dai, G Xiong, S Lan, C Zhang - Small, 2023 - Wiley Online Library
Most nanozymes in development for medical applications only exhibit single‐enzyme‐like
activity, and are thus limited by insufficient catalytic activity and dysfunctionality in complex …

Endotheliopathy in acute COVID-19 and long COVID

AG Vassiliou, CS Vrettou, C Keskinidou… - International Journal of …, 2023 - mdpi.com
The pulmonary endothelium is a highly regulated organ that performs a wide range of
functions under physiological and pathological conditions. Since endothelial dysfunction …

The general factor of psychopathology (p): Choosing among competing models and interpreting p

A Caspi, RM Houts, HL Fisher… - Clinical …, 2024 - journals.sagepub.com
Over the past 10 years, the general factor of psychopathology, p, has attracted interest and
scrutiny. We review the history of the idea that all mental disorders share something in …

The uPA/uPAR system orchestrates the inflammatory response, vascular homeostasis, and immune system in fibrosis progression

Y Kanno - International Journal of Molecular Sciences, 2023 - mdpi.com
Fibrotic diseases, such as systemic sclerosis (SSc), idiopathic pulmonary fibrosis, renal
fibrosis and liver cirrhosis are characterized by tissue overgrowth due to excessive …

Soluble urokinase plasminogen activator receptor (suPAR) independently predicts severity and length of hospitalisation in patients with COVID-19

H Enocsson, C Idoff, A Gustafsson, M Govender… - Frontiers in …, 2021 - frontiersin.org
Background: Efficient healthcare based on prognostic variables in hospitalised patients with
COVID-19 could reduce the risk of complications and death. Recently, soluble urokinase …

Comparison of C-reactive protein with distinct hyperinflammatory biomarkers in association with COVID-19 severity, mortality and SARS-CoV-2 variants

TG Paranga, M Pavel-Tanasa… - Frontiers in …, 2023 - frontiersin.org
C-reactive protein (CRP) has been one of the most investigated inflammatory-biomarkers
during the ongoing COVID-19 pandemics caused by severe acute respiratory syndrome …

[HTML][HTML] Associations between plasma inflammatory markers and psychotic disorder, depressive disorder and generalised anxiety disorder in early adulthood: A …

D Mongan, SR Susai, M Föcking, JF Byrne… - Brain, Behavior, and …, 2023 - Elsevier
Background Low-grade inflammation may occur in association with several mental disorders
of early adulthood, though associations with markers of chronic inflammation such as …

Monocyte-to-lymphocyte ratio predicts mortality and cardiovascular mortality in the general population

Y Hua, JY Sun, YX Lou, W Sun, XQ Kong - International journal of …, 2023 - Elsevier
Background Systemic chronic inflammation (SCI) is closely involved in the pathogenesis of
many diseases. This study aims to investigate the association between MLR with mortality …

The role of the plasminogen/plasmin system in inflammation of the oral cavity

T Yatsenko, M Skrypnyk, O Troyanovska, M Tobita… - Cells, 2023 - mdpi.com
The oral cavity is a unique environment that consists of teeth surrounded by periodontal
tissues, oral mucosae with minor salivary glands, and terminal parts of major salivary glands …

[HTML][HTML] Social isolation, loneliness, and inflammation: A multi-cohort investigation in early and mid-adulthood

T Matthews, LJH Rasmussen, A Ambler… - Brain, Behavior, and …, 2024 - Elsevier
Social isolation and loneliness have been associated with poor health and increased risk for
mortality, and inflammation might explain this link. We used data from the Danish TRIAGE …