Targeting the holy triangle of quorum sensing, biofilm formation, and antibiotic resistance in pathogenic bacteria

RV Sionov, D Steinberg - Microorganisms, 2022 - mdpi.com
Chronic and recurrent bacterial infections are frequently associated with the formation of
biofilms on biotic or abiotic materials that are composed of mono-or multi-species cultures of …

[HTML][HTML] Biofilms by bacterial human pathogens: Clinical relevance-development, composition and regulation-therapeutical strategies

A Schulze, F Mitterer, JP Pombo, S Schild - Microbial Cell, 2021 - ncbi.nlm.nih.gov
Notably, bacterial biofilm formation is increasingly recognized as a passive virulence factor
facilitating many infectious disease processes. In this review we will focus on bacterial …

Bacterial quorum sensing: its role in virulence and possibilities for its control

ST Rutherford, BL Bassler - Cold Spring …, 2012 - perspectivesinmedicine.cshlp.org
Quorum sensing is a process of cell–cell communication that allows bacteria to share
information about cell density and adjust gene expression accordingly. This process …

Biofilm dispersion and quorum sensing

C Solano, M Echeverz, I Lasa - Current opinion in microbiology, 2014 - Elsevier
Highlights•Biofilm development and quorum sensing are social bacterial
behaviours.•Quorum sensing regulates genes involved in biofilm development.•Quorum …

Cyclic di-GMP: the first 25 years of a universal bacterial second messenger

U Römling, MY Galperin… - … and Molecular Biology …, 2013 - Am Soc Microbiol
Twenty-five years have passed since the discovery of cyclic dimeric (3′→ 5′) GMP (cyclic
di-GMP or c-di-GMP). From the relative obscurity of an allosteric activator of a bacterial …

Living in the matrix: assembly and control of Vibrio cholerae biofilms

JK Teschler, D Zamorano-Sánchez, AS Utada… - Nature Reviews …, 2015 - nature.com
Nearly all bacteria form biofilms as a strategy for survival and persistence. Biofilms are
associated with biotic and abiotic surfaces and are composed of aggregates of cells that are …

Mechanisms Underlying Vibrio cholerae Biofilm Formation and Dispersion

JK Teschler, CD Nadell, K Drescher… - Annual Review of …, 2022 - annualreviews.org
Biofilms are a widely observed growth mode in which microbial communities are spatially
structured and embedded in a polymeric extracellular matrix. Here, we focus on the model …

Resistance of bacterial biofilms to disinfectants: a review

A Bridier, R Briandet, V Thomas, F Dubois-Brissonnet - Biofouling, 2011 - Taylor & Francis
A biofilm can be defined as a community of microorganisms adhering to a surface and
surrounded by a complex matrix of extrapolymeric substances. It is now generally accepted …

Regulation of flagellar motility during biofilm formation

SB Guttenplan, DB Kearns - FEMS microbiology reviews, 2013 - academic.oup.com
Many bacteria swim in liquid or swarm over solid surfaces by synthesizing rotary flagella.
The same bacteria that are motile also commonly form nonmotile multicellular aggregates …

Division of labor during biofilm matrix production

A Dragoš, H Kiesewalter, M Martin, CY Hsu… - Current Biology, 2018 - cell.com
Organisms as simple as bacteria can engage in complex collective actions, such as group
motility and fruiting body formation. Some of these actions involve a division of labor, where …