Anti-islet autoantibodies in type 1 diabetes
E Kawasaki - International Journal of Molecular Sciences, 2023 - mdpi.com
Anti-islet autoantibodies serve as key markers in immune-mediated type 1 diabetes (T1D)
and slowly progressive T1D (SPIDDM), also known as latent autoimmune diabetes in adults …
and slowly progressive T1D (SPIDDM), also known as latent autoimmune diabetes in adults …
Heat-shock proteins induce T-cell regulation of chronic inflammation
W Van Eden, R Van der Zee, B Prakken - Nature Reviews Immunology, 2005 - nature.com
Immune responses to certain heat-shock proteins (HSPs) develop in almost all inflammatory
diseases; however, the significance of such responses is only now becoming clear. In …
diseases; however, the significance of such responses is only now becoming clear. In …
A comprehensive guide to antibody and T‐cell responses in type 1 diabetes
SM Lieberman, TP DiLorenzo - Tissue antigens, 2003 - Wiley Online Library
Type 1 diabetes (T1D) is an organ‐specific autoimmune disease in which the insulin‐
producing β cells in the pancreatic islets are selectively eliminated. T cells specific for β‐cell …
producing β cells in the pancreatic islets are selectively eliminated. T cells specific for β‐cell …
Immunomodulatory therapy to preserve pancreatic β-cell function in type 1 diabetes
F Waldron-Lynch, KC Herold - Nature Reviews Drug Discovery, 2011 - nature.com
Type 1 diabetes is a common, severe chronic autoimmune disease that is characterized by
the progressive and insidious loss of self-tolerance to the insulin-producing pancreatic islet …
the progressive and insidious loss of self-tolerance to the insulin-producing pancreatic islet …
[HTML][HTML] Antibodies against heat shock proteins in environmental stresses and diseases: friend or foe?
T Wu, RM Tanguay - Cell stress & chaperones, 2006 - ncbi.nlm.nih.gov
Heat shock proteins (Hsps) can be found in two forms, intracellular and extracellular. The
intracellular Hsps are induced as a result of stress and have been found to be cytoprotective …
intracellular Hsps are induced as a result of stress and have been found to be cytoprotective …
A common repertoire of autoantibodies is shared by cancer and autoimmune disease patients: Inflammation in their induction and impact on tumor growth
The repertoire of autoantibodies found in cancer patients partly overlaps with that typical of
patients with autoimmune diseases. Beside the biochemical and immunological properties …
patients with autoimmune diseases. Beside the biochemical and immunological properties …
Treatment of new‐onset type 1 diabetes with peptide DiaPep277® is safe and associated with preserved beta‐cell function: extension of a randomized, double‐blind …
I Raz, A Avron, M Tamir, M Metzger… - Diabetes/metabolism …, 2007 - Wiley Online Library
Abstract Background Treatment with DiaPep277®, a peptide derived from HSP60, has been
shown to preserve beta‐cell function in non‐obese diabetic mouse (NOD) mice and in a trial …
shown to preserve beta‐cell function in non‐obese diabetic mouse (NOD) mice and in a trial …
The role of heat shock proteins in type 1 diabetes
ASM Moin, M Nandakumar, A Diane, M Dehbi… - Frontiers in …, 2021 - frontiersin.org
Type 1 diabetes (T1D) is a T-cell mediated autoimmune disease characterized by
recognition of pancreatic β-cell proteins as self-antigens, called autoantigens (AAgs) …
recognition of pancreatic β-cell proteins as self-antigens, called autoantigens (AAgs) …
[HTML][HTML] A master autoantigen-ome links alternative splicing, female predilection, and COVID-19 to autoimmune diseases
JY Wang, MW Roehrl, VB Roehrl, MH Roehrl - Journal of Translational …, 2022 - Elsevier
Chronic and debilitating autoimmune sequelae pose a grave concern for the post-COVID-19
pandemic era. Based on our discovery that the glycosaminoglycan dermatan sulfate (DS) …
pandemic era. Based on our discovery that the glycosaminoglycan dermatan sulfate (DS) …
Heat shock proteins (HSPs) in the homeostasis of regulatory T cells (Tregs)
T Koliński, N Marek-Trzonkowska… - … European Journal of …, 2016 - termedia.pl
Heat shock proteins (HSPs) belong to the family of conservative polypeptides with a high
homology of the primary structure. The uniqueness of this family lies in their ability to interact …
homology of the primary structure. The uniqueness of this family lies in their ability to interact …