Ankyrin repeat proteins are found in all three kingdoms of life. Fundamentally, these proteins
are involved in protein-protein interaction in order to activate or suppress biological …

Gankyrin is a new oncoprotein with potent cell cycle and apoptotic properties that is
overexpressed early in hepatocarcinogenesis and in hepatocellular carcinomas. Gankyrin …

Abstract Helicobacter pylori and Epstein Barr virus (EBV) are group1 carcinogens and their
role in Gastric cancer (GC) is well established. Previously we have shown that H. pylori and …

Previous studies in our laboratory have suggested that gankyrin expression is correlated
with a malignant phenotype in colorectal cancer. Here, we investigated the possible role of …

Gankyrin, a small and highly conserved protein which is identical to the p28 gene product,
was found to be related with the malignant phenotypes in liver and esophageal carcinoma …

Gankyrin is an oncoprotein composed of six ankyrin repeats, over-expressed in the
Hepatocellular Carcinoma (HCC), and directly involved in the cell cycle regulation …

Gankyrin is an oncoprotein commonly overexpressed in most hepatocellular carcinomas.
Gankyrin interacts with S6 ATPase of the 19S regulatory particle of the 26S proteasome and …

To elucidate the possible involvement of gankyrin in ESCC progression and the effect of its
down‐regulation in ESCC, we investigated the expression of gankyrin in ESCC tissues …

Background The availability of suitable recombinant protein is still a major bottleneck in
protein structure analysis. The Protein Structure Factory, part of the international structural …

Gankyrin is a subunit of the 26S proteasome, and has been known to degrade p53 and
retinoblastoma protein and promote the tumorigenicity and metastasis in some …