Uterine fibroids are benign monoclonal neoplasms of the myometrium, representing the
most common tumors in women worldwide. To date, no long-term or noninvasive treatment …

The use of biomarkers in diagnosis, therapy and prognosis has gained increasing interest
over the last decades. In particular, the analysis of biomarkers in cancer patients within the …

Metastatic cancer is almost always terminal, and more than 90% of cancer deaths result from
metastatic disease. Combating cancer metastasis and post-therapeutic recurrence …

Therapeutic resistance and metastatic progression are responsible for the majority of cancer
mortalities. In particular, the development of resistance is a significant barrier to the efficacy …

The growth of cancer tissue is thought to be considered driven by a small subpopulation of
cells, so-called cancer stem cells (CSCs). CSCs are located at the apex of a hierarchy in a …

Over the last decades, the cancer survival rate has increased due to personalized therapies,
the discovery of targeted therapeutics and novel biological agents, and the application of …

Cancer stem cells (CSCs) are a small population of malignant cells that induce tumor onset
and development. CSCs share similar features with normal stem cells in the case of self …

Background. The term 'cancer'often describes malignant tumors. The issue of cancerous
stem cells is not a novelty but has existed for centuries. Different civilizations have handled …

Despite great strides being achieved in improving cancer patients' outcomes through better
therapies and combinatorial treatment, several hurdles still remain due to therapy …

The emerging concept of cancer stem cells (CSCs) as the key driver behind carcinogenesis,
progression, and diversity has displaced the prior model of a tumor composed of cells with …