During the past decades, synthetic organic chemistry discovered that directing group
assisted C–H activation is a key tool for the expedient and siteselective construction of C–C …

Transition metal-catalyzed direct functionalization of C–H bonds is one of the key emerging
strategies that is currently attracting tremendous attention with the aim to provide alternative …

C H bonds are ubiquitous in organic compounds. It would, therefore, appear that direct
functionalization of substrates by activation of C H bonds would eliminate the multiple …

C‐H‐Bindungen sind in organischen Verbindungen allgegenwärtig. Daher erscheint die
direkte Funktionalisierung von Substraten durch Aktivierung von C‐H‐Bindungen als eine …

We report an efficient method for the alkylation of γ-C (sp3)–H bonds of picolinamide-
protected aliphatic amine substrates with primary alkyl iodides via palladium catalysis …

The scope of palladium-catalyzed, auxiliary-assisted direct arylation and alkylation of sp2
and sp3 C–H bonds of amine and carboxylic acid derivatives has been investigated. The …

Over the last two decades, the use of metal-mediated direct CÀH functionalization has
grown rapidly as it enables the conversion of ubiquitous CÀH bonds of organic molecules …

A Pd-catalyzed amide-directed enantioselective hydrocarbofunctionalization of unactivated
alkenes with C–H nucleophiles has been developed using a chiral monodentate oxazoline …

Selective cyclization and substitution was achieved with designated 1, 2, 3-triazole acid
auxiliary groups under Pd catalyzed C–H activation conditions. Both sp2 and sp3 C–H …

Lanthanum trifluoromethanesulfonate is an effective single-component catalyst for
synthesizing a variety of amides directly from esters and amines under mild conditions …