Integral membrane proteins (IMPs) lie at the critical junctions between intracellular
compartments and cells and their environment. As such, IMPs are in a unique position to …

Mass spectrometry-based proteomics is a sophisticated identification tool specializing in
portraying protein dynamics at a molecular level. Proteomics provides biologists with a …

Mass spectrometry has enabled the study of cellular signaling on a systems-wide scale,
through the quantification of post-translational modifications, such as protein …

Climate change is expected to alter the geographic distribution of wildfire, a complex abiotic
process that responds to a variety of spatial and environmental gradients. How future climate …

With increasing energy prices and the drive to reduce CO2 emissions, food industries are
challenged to find new technologies in order to reduce energy consumption, to meet legal …

We have developed a new protocol for digesting hydrophobic proteins using trypsin with the
aid of phase-transfer surfactants (PTS), such as sodium deoxycholate (SDC). SDC increases …

Enzymatic digestion for protein sequencing usually requires much time, and does not
always result in high sequence coverage. Here we report the use of aqueous microdroplets …

Improved in-solution tryptic digestion of proteins in terms of speed and peptide coverage
was achieved with the aid of a novel acid-labile anionic surfactant (ALS). Unlike SDS, ALS …

Plasma biomarkers studies are based on the differential expression of proteins between
different treatment groups or between diseased and control populations. Most mass …

Mitochondria control eukaryotic cell fate by producing the energy needed to support life and
the signals required to execute programed cell death. The biochemical milieu is known to …