[HTML][HTML] Helicobacter pylori Virulence Factors—Mechanisms of Bacterial Pathogenicity in the Gastric Microenvironment

J Baj, A Forma, M Sitarz, P Portincasa, G Garruti… - Cells, 2020 - mdpi.com
Gastric cancer constitutes one of the most prevalent malignancies in both sexes; it is
currently the fourth major cause of cancer-related deaths worldwide. The pathogenesis of …

YAP/TAZ: drivers of tumor growth, metastasis, and resistance to therapy

BJ Thompson - Bioessays, 2020 - Wiley Online Library
The transcriptional co‐activators YAP (or YAP1) and TAZ (or WWTR1) are frequently
activated during the growth and progression of many solid tumors, including lung, colorectal …

[HTML][HTML] Gut microbiome in gastrointestinal cancer: a friend or foe?

Y Liu, Y Baba, T Ishimoto, X Gu, J Zhang… - … Journal of Biological …, 2022 - ncbi.nlm.nih.gov
The impact of the gut microbiome on host health is becoming increasingly recognized. To
date, there is growing evidence that the complex characteristics of the microbial community …

[HTML][HTML] Gastric cancer: advances in carcinogenesis research and new therapeutic strategies

L Seeneevassen, E Bessède, F Mégraud… - International journal of …, 2021 - mdpi.com
Gastric cancer's bad incidence, prognosis, cellular and molecular heterogeneity amongst
others make this disease a major health issue worldwide. Understanding this affliction is a …

[HTML][HTML] Helicobacter pylori Virulence Factors Exploiting Gastric Colonization and its Pathogenicity

S Ansari, Y Yamaoka - Toxins, 2019 - mdpi.com
Helicobacter pylori colonizes the gastric epithelial cells of at least half of the world's
population, and it is the strongest risk factor for developing gastric complications like chronic …

[HTML][HTML] Mechanisms of the Epithelial–Mesenchymal Transition and Tumor Microenvironment in Helicobacter pylori-Induced Gastric Cancer

J Baj, I Korona-Głowniak, A Forma, A Maani, E Sitarz… - Cells, 2020 - mdpi.com
Helicobacter pylori (H. pylori) is one of the most common human pathogens, affecting half of
the world's population. Approximately 20% of the infected patients develop gastric ulcers or …

[HTML][HTML] Hippo pathway dysregulation in gastric cancer: from Helicobacter pylori infection to tumor promotion and progression

B Messina, F Lo Sardo, S Scalera, L Memeo… - Cell Death & …, 2023 - nature.com
The Hippo pathway plays a critical role for balancing proliferation and differentiation, thus
regulating tissue homeostasis. The pathway acts through a kinase cascade whose final …

The deadly cross-talk between Hippo pathway and epithelial–mesenchymal transition (EMT) in cancer

I Akrida, V Bravou, H Papadaki - Molecular Biology Reports, 2022 - Springer
Hippo signaling pathway is an evolutionarily conserved network that regulates organ size
growth and tissue regeneration. Hippo signaling dysfunction results in uncontrolled cell …

[HTML][HTML] Helicobacter pylori Virulence Factor Cytotoxin-Associated Gene A (CagA)-Mediated Gastric Pathogenicity

S Ansari, Y Yamaoka - International journal of molecular sciences, 2020 - mdpi.com
Helicobacter pylori causes persistent infection in the gastric epithelium of more than half of
the world's population, leading to the development of severe complications such as peptic …

[HTML][HTML] The role of photoactivated and non-photoactivated verteporfin on tumor

C Wei, X Li - Frontiers in pharmacology, 2020 - frontiersin.org
Verteporfin (VP) has long been clinically used to treat age-related macular degeneration
(AMD) through photodynamic therapy (PDT). Recent studies have reported a significant anti …