Exhaled markers of pulmonary disease

SA Kharitonov, PJ Barnes - … journal of respiratory and critical care …, 2001 - atsjournals.org
There has recently been an explosion of interest in the analysis of breath constituents as a
way of monitoring inflammation and oxidative stress in the lungs. Here we review the use of …

Environmental influences on childhood asthma: Allergens

A Custovic, AP de Moira, CS Murray… - Pediatric Allergy and …, 2023 - Wiley Online Library
Allergen exposure is associated with the development of allergen‐specific sensitization, but
their relationship is influenced by other contemporaneous exposures (such as microbial …

Use of fractional exhaled nitric oxide to guide the treatment of asthma: an official American Thoracic Society clinical practice guideline

SB Khatri, JM Iaccarino, A Barochia… - American journal of …, 2021 - atsjournals.org
Background: The fractional exhaled nitric oxide (FeNO) test is a point-of-care test that is
used in the assessment of asthma. Objective: To provide evidence-based clinical guidance …

Synergism between allergens and viruses and risk of hospital admission with asthma: case-control study

RM Green, A Custovic, G Sanderson, J Hunter… - Bmj, 2002 - bmj.com
Objective: To investigate the importance of sensitisation and exposure to allergens and viral
infection in precipitating acute asthma in adults resulting in admission to hospital. Design …

Biomarkers of some pulmonary diseases in exhaled breath

SA Kharitonov, PJ Barnes - Biomarkers, 2002 - Taylor & Francis
Analysis of various biomarkers in exhaled breath allows completely non-invasive monitoring
of inflammation and oxidative stress in the respiratory tract in inflammatory lung diseases …

Clinical aspects of exhaled nitric oxide

SA Kharitonov, PJ Barnes - European Respiratory Journal, 2000 - Wiley Online Library
There has been intense research into the role nitric oxide (NO) plays in physiological and
pathological mechanisms and its clinical significance in respiratory medicine. Elevated …

Measurement of exhaled nitric oxide in children, 2001: E. Baraldi and JC de Jongste on behalf of the Task Force

E Baraldi, JC De Jongste, B Gaston… - European …, 2002 - Eur Respiratory Soc
Measurement of fractional exhaled nitric oxide in exhaled air is an exciting innovative
technique that gives new insights in to the pathophysiology of lung disease and asthma in …

Exposure and sensitization to indoor allergens: association with lung function, bronchial reactivity, and exhaled nitric oxide measures in asthma

SJ Langley, S Goldthorpe, M Craven, J Morris… - Journal of allergy and …, 2003 - Elsevier
Background: Exposure to high levels of allergens in sensitized asthmatic patients causes
worsening of pulmonary function in experimental studies. Chronic exposure to lower …

Allergens, viruses, and asthma exacerbations

CS Murray, A Simpson, A Custovic - Proceedings of the American …, 2004 - atsjournals.org
In adults and children with asthma, viral infections (rhinovirus [RV] infection being the most
prevalent) will often trigger an increase in symptomatology. The mechanisms responsible for …

Birth cohorts in asthma and allergic diseases: report of a NIAID/NHLBI/MeDALL joint workshop

J Bousquet, JE Gern, FD Martinez, JM Anto… - Journal of Allergy and …, 2014 - Elsevier
Population-based birth cohorts on asthma and allergies increasingly provide new insights
into the development and natural history of the diseases. More than 130 birth cohorts …