Background Despite best-possible medical management, many patients with end-stage
cancer experience breathlessness, especially towards the end of their lives. We assessed …

Background Older people with noncancer conditions are less likely to be referred to
palliative care services due to the inherent uncertain disease trajectory and a lack of …

Objective Cancer cachexia occurs in 30-80% of patients, increasing morbidity and mortality
and impacting the health-related quality of life also for caregivers. Pharmacological …

Objective For patients with advanced cancer, pain is a common and debilitating symptom
that can negatively impact physical, emotional, and spiritual wellbeing. This trial examined …

Control interventions (often called “sham,”“placebo,” or “attention controls”) are essential for
studying the efficacy or mechanism of physical, psychological, and self-management …

PURPOSE: African American patients with cancer underutilize advance care planning (ACP)
and palliative care (PC). This feasibility study investigated whether community health …

Background: Missing data can introduce bias and reduce the power, precision and
generalisability of study findings. Guidelines on how to address missing data are limited in …

Background: Within palliative care research, best practice guidelines to conduct scientifically
rigorous clinical trials for neurodegenerative diseases are underexplored. This patient …

Background Longitudinal observational cohort studies in cancer patients are important to
move research and clinical practice forward. Continued study participation (study retention) …

Background Attrition is a major obstacle for lifestyle interventions sustained for the medium-
to-long term and can have significant consequences on the internal validity of a trial. When …