Although archaea, Gram‐negative bacteria, and mammalian cells constitutively secrete
membrane vesicles (MVs) as a mechanism for cell‐free intercellular communication, this …

Abstract The Gram‐positive bacterium Staphylococcus aureus is a wide spread
opportunistic pathogen that can cause a range of life‐threatening diseases. To obtain a …

In the three domains of life, the Sec, YidC/Oxa1, and Tat translocases play important roles in
protein translocation across membranes and membrane protein insertion. While extensive …

Short antimicrobial peptides rich in arginine (R) and tryptophan (W) interact with
membranes. To learn how this interaction leads to bacterial death, we characterized the …

Bacterial magnetosomes are membrane-enveloped, nanometer-sized crystals of magnetite,
which serve for magnetotactic navigation. All genes implicated in the synthesis of these …

Functional genomics of the Gram-positive model organism Bacillus subtilis reveals valuable
insights into basic concepts of cell physiology. In this study, we monitor temporal changes in …

In its natural habitats, Bacillus subtilis is exposed to changing osmolarity, necessitating
adaptive stress responses. Transcriptomic and proteomic approaches can provide a picture …

The genome sequence is the “blue-print of life,” but proteomics provides the link to the actual
physiology of living cells. Because of their low complexity bacteria are excellent model …

Cellular energy generation uses membrane-localized electron transfer chains for ATP
synthesis. Formed ATP in turn is consumed for the biosynthesis of cellular building blocks. In …

Proteolytic treatment of intact bacterial cells is an ideal means for identifying surface‐
exposed peptide epitopes and has potential for the discovery of novel vaccine targets. Cell …