Autoimmune diseases affect up to 10% of the world's population and, as a whole, they are
far more common in females, although differences exist according to the single disease and …

BD is a systemic inflammatory disease with a variable vasculitis. Paediatric onset is very rare
and carries a strong genetic component. Oral ulcers and fever of unknown origin are …

Objectives The association between mutations in TNFAIP3, encoding the NF-kB regulatory
protein A20, and a new autoinflammatory disease has recently been recognised. This study …

The cryopyrin-associated periodic syndrome (CAPS) is a severity spectrum of rare diseases.
CAPS comprises the three conditions previously described as familial cold autoinflammatory …

Uveitis is less common in children than in adults, and its diagnosis and management can be
particularly challenging. Young children are often asymptomatic either because of inability to …

Behçet's disease (BD) is a systemic variable vessel vasculitis that involves the skin, mucosa,
joints, eyes, arteries, veins, nervous system and gastrointestinal system, presenting with …

Behçet's Disease (BD) is a systemic vasculitis firstly described as a disorder causing
aphthous lesion in oral and genital mucosae and uveitis. The disease has an extremely …

Behcet's syndrome (BS) is a vasculitis, seen more commonly around the Mediterranean and
the Far East, and manifests with oral and genital ulcerations, skin lesions, uveitis, and …

There are currently limited data regarding paediatric Behçet's disease (BD), particularly in
the UK. We describe the clinical spectrum, treatment and outcome of BD, and explore the …

Autoinflammatory diseases (AIDs) are a genetically heterogeneous group of diseases
caused by mutations of genes encoding proteins, which play a pivotal role in the regulation …