Cardiac injury remains a major cause of morbidity and mortality worldwide. Despite
significant advances, a full understanding of why the heart fails to fully recover function after …

Recent advances have greatly improved our understanding of the molecular mechanisms
behind atherosclerosis pathogenesis. However, there is still a need to systematize this data …

Caspase-9, a cysteine-aspartic protease known for its role as an initiator of intrinsic
apoptosis, regulates physiological cell death and pathological tissue degeneration. Its …

Research showing that microRNAs (miRNAs) are versatile regulators of gene expression
has instigated tremendous interest in cardiovascular research. The overwhelming majority of …

The heart contains a population of resident macrophages that markedly expands following
injury through recruitment of monocytes and through proliferation of macrophages. In …

Vascular disease was for a long time considered a disease of the old age, but it is becoming
increasingly clear that a cumulus of factors can cause early vascular aging (EVA) …

The gut microbiota is critical to human health, such as digesting nutrients, forming the
intestinal epithelial barrier, regulating immune function, producing vitamins and hormones …

Despite recent scientific and technological advances, myocardial infarction (MI) still
represents a major global health problem, leading to high morbidity and mortality worldwide …

Atherosclerosis, one of the life-threatening cardiovascular diseases (CVDs), has been
demonstrated to be a chronic inflammatory disease, and inflammatory and immune …

Background The drive to vaccinate large populations is nowadays the main instrument for
combating the pandemic and preventing serious disease and death. However, breakthrough …