Organoids are three‐dimensional (3D) miniaturized versions of organs or tissues that are
derived from cells with stem potential and can self‐organize and differentiate into 3D cell …

Tremendous progress has been made in the field of toxicology leading to the advance of
developmental toxicity assessment. Conventional animal models and in vitro two …

The potential uses of graphene-based nanomaterials (NMs) in various fields lead to the
concern about their neurotoxicity, considering that graphene-based NMs are capable to …

An increasing number of harmful environmental factors are causing serious impacts on
human health, and there is an urgent need to accurately identify the toxic effects and …

Thanks to progress in the development of three‐dimensional (3D) culture technologies,
human central nervous system (CNS) development and diseases have been gradually …

Silver nanoparticles (AgNPs) are used in various research fields. Although the neurotoxicity
of AgNPs has been explored in animal models and 2D cell-culture models, including human …

Neurotoxicity studies aim at understanding the toxic effects and mechanisms of toxicants to
human central nervous systems (CNS). However, human brains are the most complex …

Polybrominated diphenyl ethers (PBDEs) serve as brominated flame retardants which
continue to receive considerable attention because of their persistence, bioaccumulation …

Abstract Di-(2-ethylhexyl) phthalate (DEHP), a ubiquitous environmental endocrine
disruptor, is widely used in consumer products. Increasing evidence implies that DEHP …

Perfluorooctane sulfonate (PFOS), a class of synthetic chemicals detected in various
environmental compartments, has been associated with dysfunctions of the human central …