Cellular immune responses in the pathophysiology of preeclampsia
Preeclampsia, defined as new-onset hypertension accompanied by proteinuria occurring at
20 weeks of gestation or later, is a leading cause of perinatal morbidity and mortality …
20 weeks of gestation or later, is a leading cause of perinatal morbidity and mortality …
The role of the immune system in preeclampsia
S Saito, A Shiozaki, A Nakashima, M Sakai… - Molecular aspects of …, 2007 - Elsevier
Recent data demonstrate that an altered immune response may play a key role in the
development of preeclampsia. Some epidemiological findings and animal models support …
development of preeclampsia. Some epidemiological findings and animal models support …
Th1/Th2 balance in preeclampsia
S Saito, M Sakai - Journal of reproductive immunology, 2003 - Elsevier
The syndrome of preeclampsia has previously been ascribed to generalized maternal
endothelial dysfunction, poor placentation and excessive maternal inflammatory response …
endothelial dysfunction, poor placentation and excessive maternal inflammatory response …
Animal models of preeclampsia: causes, consequences, and interventions
Preeclampsia is a common pregnancy complication, affecting 2% to 8% of pregnancies
worldwide, and is an important cause of both maternal and fetal morbidity and mortality …
worldwide, and is an important cause of both maternal and fetal morbidity and mortality …
TH1/TH2 paradigm in pregnancy: paradigm lost? Cytokines in pregnancy/early abortion: reexamining the TH1/TH2 paradigm
G Chaouat, N Ledée-Bataille, S Dubanchet… - International archives of …, 2004 - karger.com
In this paper, we briefly survey the history of concepts in reproductive immunology from
antibody-mediated tolerance to the 'fetal allograft'to the current concept of an embryo …
antibody-mediated tolerance to the 'fetal allograft'to the current concept of an embryo …
T-helper-1 and T-helper-2 responses in psychiatric disorders
MJ Schwarz, S Chiang, N Müller… - Brain, behavior, and …, 2001 - Elsevier
The expanding field of psychoneuroimmunology has markedly increased knowledge about
the interference of the central nervous system and the immune system. Immunological …
the interference of the central nervous system and the immune system. Immunological …
Th1/Th2 cytokines balance—yin and yang of reproductive immunology
JR Wilczyński - European Journal of Obstetrics & Gynecology and …, 2005 - Elsevier
For years conception of Th2 overbalance during pregnancy has been a paradigm for
immunology of reproduction, while Th1 activity has been presented as unwanted …
immunology of reproduction, while Th1 activity has been presented as unwanted …
Is inflammation the cause of pre-eclampsia?
It has been proposed that either excessive inflammation or an imbalance in angiogenic
factors cause pre-eclampsia. In the present review, the arguments for and against the role of …
factors cause pre-eclampsia. In the present review, the arguments for and against the role of …
Immunological analogy between allograft rejection, recurrent abortion and pre-eclampsia–the same basic mechanism?
JR Wilczyński - Human immunology, 2006 - Elsevier
There are still controversies concerning the role of immunological mechanisms engaged
both in recurrent abortions (RA) and pre-eclampsia (PE). According to some opinions …
both in recurrent abortions (RA) and pre-eclampsia (PE). According to some opinions …
Maternal microbiome in preeclampsia pathophysiology and implications on offspring health
JA Ishimwe - Physiological reports, 2021 - Wiley Online Library
Preeclampsia is a devastating hypertensive pregnancy disorder that currently affects 2%–
8% of pregnancies worldwide. It is associated with maternal and fetal mortality and morbidity …
8% of pregnancies worldwide. It is associated with maternal and fetal mortality and morbidity …