Pharmaceutical and medicinal significance of sulfur (SVI)-Containing motifs for drug discovery: A critical review
Sulfur (S VI) based moieties, especially, the sulfonyl or sulfonamide based analogues have
showed a variety of pharmacological properties, and its derivatives propose a high degree …
showed a variety of pharmacological properties, and its derivatives propose a high degree …
Indole derivatives as anti-tubercular agents: An overview on their synthesis and biological activities
Background: The indole framework is considered as one of the privileged structures in the
area of medicinal chemistry and drug discovery because compounds containing this …
area of medicinal chemistry and drug discovery because compounds containing this …
Byproduct promoted regioselective sulfenylation of indoles with sulfinic acids
CR Liu, LH Ding - Organic & biomolecular chemistry, 2015 - pubs.rsc.org
An unprecedented method to synthesise 3-sulfenylindoles is demonstrated via byproduct
promoted sulfenylation of indoles with sulfinic acids in the absence of an external catalyst …
promoted sulfenylation of indoles with sulfinic acids in the absence of an external catalyst …
Base-mediated chalcogenoaminative annulation of 2-alkynylanilines for direct access to 3-sulfenyl/selenyl-1 H-indoles
WC Chen, R Bai, WL Cheng, CY Peng… - Organic & …, 2023 - pubs.rsc.org
An efficient and transition metal-free synthesis of 3-sulfenyl/selenyl-1H-indoles via a base-
assisted chalcogenoaminative annulation of 2-alkynyl aniline with disulfides/diselenides is …
assisted chalcogenoaminative annulation of 2-alkynyl aniline with disulfides/diselenides is …
Seeking potent anti-tubercular agents: Design, synthesis, anti-tubercular activity and docking study of various ((triazoles/indole)-piperazin-1-yl/1, 4-diazepan-1-yl) …
KM Naidu, S Srinivasarao, N Agnieszka, AK Ewa… - Bioorganic & medicinal …, 2016 - Elsevier
A series of thirty eight novel 3-(4-((substituted-1H-1, 2, 3-triazol-4-yl) methyl) piperazin-1-
yl/1, 4-diazepan-1-yl) benzo [d] isoxazole and 1-(4-(benzo [d] isoxazol-3-yl) piperazin-1-yl/1 …
yl/1, 4-diazepan-1-yl) benzo [d] isoxazole and 1-(4-(benzo [d] isoxazol-3-yl) piperazin-1-yl/1 …
[HTML][HTML] Indole: A promising scaffold for the discovery and development of potential anti-tubercular agents
Indole-containing small molecules have been reported to have diverse pharmacological
activities. The aromatic heterocyclic scaffold, which resembles various protein structures …
activities. The aromatic heterocyclic scaffold, which resembles various protein structures …
Visible light-induced tandem oxidative cyclization of 2-alkynylanilines with disulfides (diselenides) to 3-sulfenyl-and 3-selenylindoles under transition metal-free and …
Q Shi, P Li, Y Zhang, L Wang - Organic Chemistry Frontiers, 2017 - pubs.rsc.org
A simple and efficient strategy for the synthesis of 3-sulfenyl and 3-selenyl indoles via a
visible light-induced tandem cyclization of 2-alkynylanilines with disulfides (diselenides) was …
visible light-induced tandem cyclization of 2-alkynylanilines with disulfides (diselenides) was …
Synthesis of 2‐Substituted Indoles through Visible Light‐Induced Photocatalytic Cyclizations of Styryl Azides
XD Xia, J Xuan, Q Wang, LQ Lu… - … Synthesis & Catalysis, 2014 - Wiley Online Library
A visible light‐induced photocatalytic intramolecular cyclization of styryl azides has been
developed in the presence of the ruthenium complex Ru (bpy) 3Cl2 (0.5 mol%) as …
developed in the presence of the ruthenium complex Ru (bpy) 3Cl2 (0.5 mol%) as …
Wang resin catalysed sonochemical synthesis of pyrazolo [4, 3-d] pyrimidinones and 2, 3-dihydroquinazolin-4 (1H)-ones: Identification of chorismate mutase inhibitors …
The enzyme chorismate mutase (or CM that is vital for the survival of bacteria) is an
interesting pharmacological target for the identification of new anti-tubercular agents. The 5 …
interesting pharmacological target for the identification of new anti-tubercular agents. The 5 …
Ultrasound-based approach to spiro-2, 3-dihydroquinazolin-4 (1H)-ones: their in vitro evaluation against chorismate mutase
D Rambabu, SK Kumar, BY Sreenivas, S Sandra… - Tetrahedron …, 2013 - Elsevier
Amberlyst-15 has been identified as a green and reusable catalyst in the synthesis of spiro
2, 3-dihydroquinazolin-4 (1H)-ones under ultrasound irradiation at room temperature. The …
2, 3-dihydroquinazolin-4 (1H)-ones under ultrasound irradiation at room temperature. The …