Pirfenidone (PFD) is a pharmacological compound with therapeutic efficacy in idiopathic
pulmonary fibrosis. It has been chiefly characterized as an antifibrotic agent, although it was …

Idiopathic pulmonary fibrosis (IPF) is a chronic fibrosing lung disease of indeterminate
etiology and limited therapeutic options. The initiation, development, and progression of IPF …

Background: This American Thoracic Society, European Respiratory Society, Japanese
Respiratory Society, and Asociación Latinoamericana de Tórax guideline updates prior …

Background: This guideline addresses the diagnosis of hypersensitivity pneumonitis (HP). It
represents a collaborative effort among the American Thoracic Society, Japanese …

A subset of individuals who recover from coronavirus disease 2019 (COVID-19) develop
post-acute sequelae of severe acute respiratory syndrome coronavirus 2 (SARS-CoV …

Background: The presence of emphysema is relatively common in patients with fibrotic
interstitial lung disease. This has been designated combined pulmonary fibrosis and …

We used data from the INBUILD and INPULSIS trials to investigate the natural history of
progressive fibrosing interstitial lung diseases (ILDs). Subjects in the two INPULSIS trials …

Objective We provide evidence‐based recommendations regarding screening for interstitial
lung disease (ILD) and the monitoring for ILD progression in people with systemic …

Ontologically distinct populations of macrophages differentially contribute to organ fibrosis
through unknown mechanisms. We applied lineage tracing, single-cell RNA sequencing …

Rationale: Idiopathic pulmonary fibrosis (IPF) is a complex lung disease characterized by
scarring of the lung that is believed to result from an atypical response to injury of the …