Interplay between Janus kinase/signal transducer and activator of transcription signaling activated by type I interferons and viral antagonism

Y Nan, C Wu, YJ Zhang - Frontiers in immunology, 2017 - frontiersin.org
Interferons (IFNs), which were discovered a half century ago, are a group of secreted
proteins that play key roles in innate immunity against viral infection. The major signaling …

Decoding the role of miRNAs in oral cancer pathogenesis: A focus on signaling pathways

AS Doghish, AA El-Husseiny, EG Khidr… - … -Research and Practice, 2023 - Elsevier
Oral cancer (OC) is the predominant type originating in the head and neck region. The
incidence of OC is mostly associated with behavioral risk factors, including tobacco smoking …

Smoking‐induced M2‐TAMs, via circEML4 in EVs, promote the progression of NSCLC through ALKBH5‐regulated m6A modification of SOCS2 in NSCLC cells

C Cheng, P Wang, Y Yang, X Du, H Xia, J Liu… - Advanced …, 2023 - Wiley Online Library
Lung cancer is a commonly diagnosed disease worldwide, with non‐small cell lung cancers
(NSCLCs) accounting for≈ 85% of cases. Cigarette smoke is an environmental exposure …

MiRNA-related metastasis in oral cancer: moving and shaking

M Eslami, S Khazeni, XM Khanaghah, MH Asadi… - Cancer cell …, 2023 - Springer
Across the world, oral cancer is a prevalent tumor. Over the years, both its mortality and
incidence have grown. Oral cancer metastasis is a complex process involving cell invasion …

MicroRNAs as modulators of oral tumorigenesis—A focused review

K Rishabh, S Khadilkar, A Kumar, I Kalra… - International journal of …, 2021 - mdpi.com
Oral cancers constitute the majority of head and neck tumors, with a relatively high incidence
and poor survival rate in developing countries. While the five-year survival rates of the oral …

[HTML][HTML] LncRNA MEG3 targeting miR-424-5p via MAPK signaling pathway mediates neuronal apoptosis in ischemic stroke

Y Xiang, Y Zhang, Y Xia, H Zhao, A Liu… - Aging (Albany NY …, 2020 - ncbi.nlm.nih.gov
Emerging evidence suggests that long non-coding RNAs (lncRNAs) are significant
regulators in the pathological process of ischemic stroke (IS). However, little is known about …

Digesting the role of JAK-STAT and cytokine signaling in oral and gastric cancers

Y Ni, JT Low, J Silke, LA O'Reilly - Frontiers in Immunology, 2022 - frontiersin.org
When small proteins such as cytokines bind to their associated receptors on the plasma
membrane, they can activate multiple internal signaling cascades allowing information from …

MiR-30a and miR-379 modulate retinoic acid pathway by targeting DNA methyltransferase 3B in oral cancer

SG Shiah, JR Hsiao, HJ Chang, YM Hsu… - Journal of biomedical …, 2020 - Springer
Background Epigenetic silencing of retinoic acid (RA) signaling-related genes have been
linked with the pathogenesis and clinical outcome in oral squamous cell carcinoma (OSCC) …

IL-8 secreted from M2 macrophages promoted prostate tumorigenesis via STAT3/MALAT1 pathway

T Zheng, G Ma, M Tang, Z Li, R Xu - International Journal of Molecular …, 2018 - mdpi.com
Prostate cancer (PCa) is a major health problem in males. Metastasis-associated with lung
adenocarcinoma transcript-1 (MALAT1), which is overexpressed in PCa tissue, is associated …

H19X-encoded miR-424 (322)/-503 cluster: emerging roles in cell differentiation, proliferation, plasticity and metabolism

F Wang, R Liang, N Tandon, ER Matthews… - Cellular and Molecular …, 2019 - Springer
Abstract miR-424 (322)/-503 are mammal-specific members of the extended miR-15/107
microRNA family. They form a co-expression network with the imprinted lncRNA H19 in …