Successful regeneration of large segmental bone defects remains a major challenge in
clinical orthopedics, thus it is of important significance to fabricate a suitable alternative …

Bone tissue engineering commonly encompasses the use of three-dimensional (3D)
scaffolds to provide a suitable microenvironment for the propagation of cells to regenerate …

In the last few years, additive manufacturing (AM) has been gaining great interest in the
fabrication of complex structures for soft-to-hard tissues regeneration, with tailored porosity …

Introduction: Years of tissue engineering research have clearly demonstrated the potential of
integrating growth factors (GFs) into scaffolds for tissue regeneration, a concept that has …

In the era of personalised medicine, novel therapeutic approaches raise increasing hopes to
address currently unmet medical needs by developing patient-customised treatments. Three …

In tissue engineering, the fate of a particular organ/tissue regeneration and repair mainly
depends on three pillars-3D architecture, cells used, and stimulus provided. 3D cell …

Collagen is a natural polymer found abundantly in the extracellular matrix (ECM). It is easily
extracted from a variety of sources and exhibits excellent biological properties such as …

Blood components play key roles in the modulation of the wound healing process and,
together with the provisional fibrin matrix ability to selectively bind bioactive molecules and …

Critical sized bone defects are difficult to manage and currently available clinical/surgical
strategies for treatment are not completely successful. Polycaprolactone (PCL) which is a …

Background: Nowadays, production of nanocomposite scaffolds based on natural
biopolymer, bioceramic, and metal ions is a growing field of research due to the potential for …