MSIGen: an open-source python package for processing and visualizing mass spectrometry imaging data
Mass spectrometry imaging (MSI) provides information about the spatial localization of
molecules in complex samples with high sensitivity and molecular selectivity. Although point …
molecules in complex samples with high sensitivity and molecular selectivity. Although point …
Untargeted Spatial Metabolomics and Spatial Proteomics on the Same Tissue Section
GW Vandergrift, M Veličković, LZ Day… - Analytical …, 2024 - ACS Publications
An increasing number of spatial multiomic workflows have recently been developed. Some
of these approaches have leveraged initial mass spectrometry imaging (MSI)-based spatial …
of these approaches have leveraged initial mass spectrometry imaging (MSI)-based spatial …
Experimental and Computational Evaluation of Lipidomic In-Source Fragmentation as a Result of Postionization with Matrix-Assisted Laser Desorption/Ionization
Matrix-assisted laser desorption/ionization mass spectrometry imaging (MALDI-MSI) can
provide spatially resolved molecular information about a sample. Recently, a postionization …
provide spatially resolved molecular information about a sample. Recently, a postionization …
Large-Scale Evaluation of Spatial Metabolomics Protocols and Technologies
V Saharuka, LM Vieira, L Stuart, M Ekelöf… - bioRxiv, 2024 - biorxiv.org
Spatial metabolomics using imaging mass spectrometry (MS) enables untargeted and label-
free metabolite mapping in biological samples. Despite the range of available imaging MS …
free metabolite mapping in biological samples. Despite the range of available imaging MS …
[HTML][HTML] MALDI-IM-MS Imaging of Brain Sterols and Lipids in a Mouse Model of Smith-Lemli-Opitz Syndrome
A Li, L Xu - bioRxiv, 2023 - ncbi.nlm.nih.gov
Abstract Smith-Lemli-Opitz syndrome (SLOS) is a neurodevelopmental disorder caused by
genetic mutations in the DHCR7 gene, encoding the enzyme 3β-hydroxysterol-Δ 7 …
genetic mutations in the DHCR7 gene, encoding the enzyme 3β-hydroxysterol-Δ 7 …
Spatial Probabilistic Mapping of Biomolecular Ensembles in Tissue via Mass Spectrometry Imaging
D Abu Sammour - 2023 - archiv.ub.uni-heidelberg.de
Tissues are a major focus of clinical research and histopathological diagnosis for a wide
range of diseases. Understanding the complex biomolecular manifestations of disease …
range of diseases. Understanding the complex biomolecular manifestations of disease …
Temporal and Spatial Multi-omics Characterization of Smith-Lemli-Opitz Syndrome
A Li - 2023 - search.proquest.com
Abstract Smith-Lemli-Opitz syndrome (SLOS) is a metabolic disorder caused by genetic
mutations in the DHCR7 gene, leading to defective 3β-hydroxysterol-Δ 7-reductase …
mutations in the DHCR7 gene, leading to defective 3β-hydroxysterol-Δ 7-reductase …