Diagnosis of autism spectrum disorder: reconciling the syndrome, its diverse origins, and variation in expression

JN Constantino, T Charman - The lancet neurology, 2016 - thelancet.com
Recent discoveries about the pathogenesis and symptom structure of autism spectrum
disorders (ASDs) are challenging traditional nosology and driving efforts to reconceptualise …

Social skills deficits in autism spectrum disorder: potential biological origins and progress in developing therapeutic agents

RE Frye - CNS drugs, 2018 - Springer
Autism spectrum disorder is defined by two core symptoms: a deficit in social communication
and the presence of repetitive behaviors and/or restricted interests. Currently, there is no US …

Functional neuroimaging of high-risk 6-month-old infants predicts a diagnosis of autism at 24 months of age

RW Emerson, C Adams, T Nishino, HC Hazlett… - Science translational …, 2017 - science.org
Autism spectrum disorder (ASD) is a neurodevelopmental disorder characterized by social
deficits and repetitive behaviors that typically emerge by 24 months of age. To develop …

Effects of bumetanide on neurobehavioral function in children and adolescents with autism spectrum disorders

E Lemonnier, N Villeneuve, S Sonie, S Serret… - Translational …, 2017 - nature.com
In animal models of autism spectrum disorder (ASD), the NKCC1 chloride-importer inhibitor
bumetanide restores physiological (Cl−) i levels, enhances GABAergic inhibition and …

Can Bayesian theories of autism spectrum disorder help improve clinical practice?

H Haker, M Schneebeli, KE Stephan - Frontiers in psychiatry, 2016 - frontiersin.org
Diagnosis and individualized treatment of autism spectrum disorder (ASD) represent major
problems for contemporary psychiatry. Tackling these problems requires guidance by a …

Selective mutism and its relations to social anxiety disorder and autism spectrum disorder

P Muris, TH Ollendick - Clinical child and family psychology review, 2021 - Springer
In current classification systems, selective mutism (SM) is included in the broad anxiety
disorders category. Indeed, there is abundant evidence showing that anxiety, and social …

Tolerability, safety, and benefits of risperidone in children and adolescents with autism: 21-month follow-up after 8-week placebo-controlled trial

M Aman, M Rettiganti, HN Nagaraja… - Journal of child and …, 2015 - liebertpub.com
Objective: Risperidone has demonstrated efficacy for acute (8 week) and intermediate
length (6 month) management of severe irritability and aggression in children and …

Validating the social responsiveness scale for adults with autism

W Chan, LE Smith, J Hong, JS Greenberg… - Autism …, 2017 - Wiley Online Library
The Social Responsiveness Scale [SRS; Constantino & Gruber, 2005] is a widely‐used
measure of autism symptoms, but its application for the study of adults with autism spectrum …

Autism‐related variation in reciprocal social behavior: A longitudinal study

RE Wagner, Y Zhang, T Gray, A Abbacchi… - Child …, 2019 - Wiley Online Library
Deficits in reciprocal social behavior are a characterizing feature of autism spectrum
disorder (ASD). Autism‐related variation in reciprocal social behavior (AVR) in the general …

A randomized, placebo-controlled trial of d-cycloserine for the enhancement of social skills training in autism spectrum disorders

NF Minshawi, LK Wink, R Shaffer, MH Plawecki… - Molecular Autism, 2016 - Springer
Background Researchers have demonstrated that d-cycloserine (DCS) can enhance the
effects of behavioral interventions in adults with anxiety and enhances prosocial behavior in …