Retinal stimulation strategies to restore vision: Fundamentals and systems

L Yue, JD Weiland, B Roska, MS Humayun - Progress in retinal and eye …, 2016 - Elsevier
Retinal degeneration, a leading cause of blindness worldwide, is primarily characterized by
the dysfunctional/degenerated photoreceptors that impair the ability of the retina to detect …

Challenges and opportunities of implantable neural interfaces: From material, electrochemical and biological perspectives

Q Zeng, Z Huang - Advanced Functional Materials, 2023 - Wiley Online Library
The desirable implantable neural interfaces can accurately record bioelectrical signals from
neurons and regulate neural activities with high spatial/time resolution, facilitating the …

Spatially patterned electrical stimulation to enhance resolution of retinal prostheses

LH Jepson, P Hottowy, K Mathieson… - Journal of …, 2014 - Soc Neuroscience
Retinal prostheses electrically stimulate neurons to produce artificial vision in people
blinded by photoreceptor degenerative diseases. The limited spatial resolution of current …

Stimulation strategies for improving the resolution of retinal prostheses

W Tong, H Meffin, DJ Garrett, MR Ibbotson - Frontiers in neuroscience, 2020 - frontiersin.org
Electrical stimulation using implantable devices with arrays of stimulating electrodes is an
emerging therapy for neurological diseases. The performance of these devices depends …

Graphene-based microelectrodes with bidirectional functionality for next-generation retinal electronic interfaces

FT Duvan, M Cunquero, E Masvidal-Codina… - Nanoscale …, 2024 - pubs.rsc.org
Neuroelectronic prostheses are being developed for restoring vision at the retinal level in
patients who have lost their sight due to photoreceptor loss. The core component of these …

Epiretinal stimulation with local returns enhances selectivity at cellular resolution

VH Fan, LE Grosberg, SS Madugula… - Journal of neural …, 2019 - iopscience.iop.org
Objective. Epiretinal prostheses are designed to restore vision in people blinded by
photoreceptor degenerative diseases, by directly activating retinal ganglion cells (RGCs) …

Improved visual acuity using a retinal implant and an optimized stimulation strategy

W Tong, M Stamp, NV Apollo, K Ganesan… - Journal of neural …, 2019 - iopscience.iop.org
Objective. Retinal prosthetic devices hold great promise for the treatment of retinal
degenerative diseases such as retinitis pigmentosa and age-related macular degeneration …

Retinal prosthetic approaches to enhance visual perception for blind patients

S Shim, K Eom, J Jeong, SJ Kim - Micromachines, 2020 - mdpi.com
Retinal prostheses are implantable devices that aim to restore the vision of blind patients
suffering from retinal degeneration, mainly by artificially stimulating the remaining retinal …

Computational challenges and opportunities for a bi-directional artificial retina

NP Shah, EJ Chichilnisky - Journal of Neural Engineering, 2020 - iopscience.iop.org
A future artificial retina that can restore high acuity vision in blind people will rely on the
capability to both read (observe) and write (control) the spiking activity of neurons using an …

The retinal response to sinusoidal electrical stimulation

P Twyford, S Fried - IEEE transactions on neural systems and …, 2015 - ieeexplore.ieee.org
Rectangular electrical pulses are the primary stimulus waveform used in retinal prosthetics
as well as many other neural stimulation applications. Unfortunately, the utility of pulsatile …