Diagnosis of bloodstream infections: an evolution of technologies towards accurate and rapid identification and antibiotic susceptibility testing

KC Tjandra, N Ram-Mohan, R Abe, MM Hashemi… - Antibiotics, 2022 - mdpi.com
Bloodstream infections (BSI) are a leading cause of death worldwide. The lack of timely and
reliable diagnostic practices is an ongoing issue for managing BSI. The current gold …

Study of Antimicrobial Resistance, Biofilm Formation, and Motility of Pseudomonas aeruginosa Derived from Urine Samples

T de Sousa, M Hébraud, O Alves, E Costa, L Maltez… - Microorganisms, 2023 - mdpi.com
Pseudomonas aeruginosa causes urinary tract infections associated with catheters by
forming biofilms on the surface of indwelling catheters. Therefore, controlling the spread of …

In vitro and in vivo antibiofilm activity of the synthetic antimicrobial peptide WLBU2 against multiple drug resistant Pseudomonas aeruginosa strains

S Masihzadeh, M Amin, Z Farshadzadeh - BMC microbiology, 2023 - Springer
Background The global crisis of antibiotic resistance increases the demand for the novel
promising alternative drugs such as antimicrobial peptides (AMPs). Here, the antibiofilm …

Antimicrobial Resistance, Genetic Lineages, and Biofilm Formation in Pseudomonas aeruginosa Isolated from Human Infections: An Emerging One Health Concern

A Silva, V Silva, M López, B Rojo-Bezares, JA Carvalho… - Antibiotics, 2023 - mdpi.com
Pseudomonas aeruginosa (PA) is a leading nosocomial pathogen and has great versatility
due to a complex interplay between antimicrobial resistance and virulence factors. PA has …

Assessment of Phage-Mediated Inhibition and Removal of Multidrug-Resistant Pseudomonas aeruginosa Biofilm on Medical Implants

S Amankwah, M Adisu, K Gorems… - Infection and Drug …, 2022 - Taylor & Francis
Purpose Despite the growing interest in bacteriophage (phage) usage for the prevention,
control, and removal of bacterial biofilms, few scientific data exist on phage applications on …

Phage-antibiotic combinations against multidrug-resistant Pseudomonas aeruginosa in in vitro static and dynamic biofilm models

DJ Holger, A El Ghali, N Bhutani, KL Lev… - Antimicrobial Agents …, 2023 - Am Soc Microbiol
Biofilm-producing Pseudomonas aeruginosa infections pose a severe threat to public health
and are responsible for high morbidity and mortality. Phage-antibiotic combinations (PACs) …

Development of sensitizer peptide-fused endolysin Lys1S-L9P acting against multidrug-resistant gram-negative bacteria

SM Son, J Kim, S Ryu - Frontiers in Microbiology, 2023 - frontiersin.org
The advent of multidrug-resistant (MDR) bacteria poses a major threat to public health,
garnering attention to novel antibiotic replacements. Endolysin, a bacteriophage-derived cell …

Proportions of Pseudomonas aeruginosa and Antimicrobial-Resistant P aeruginosa Among Patients With Surgical Site Infections in China: A Systematic Review and …

Y Yang, L Zhang, J Wang, Z Chen… - Open Forum …, 2024 - academic.oup.com
Background Pseudomonas aeruginosa is one of the most common pathogens in surgical
site infections (SSIs). However, comprehensive epidemiological and antibiotic resistance …

Ciprofloxacin in combination with bacteriophage cocktails against multi-drug resistant Pseudomonas aeruginosa in ex vivo simulated endocardial vegetation models

A El Ghali, K Stamper, AJ Kunz Coyne… - Antimicrobial Agents …, 2023 - Am Soc Microbiol
Pseudomonas aeruginosa-associated infective endocarditis represents difficult-to-treat,
deep-seated infections. Phage-antibiotic combinations have shown to eradicate multi-drug …

Synthesis of a new diarylhydrazone derivative and an evaluation of its in vitro biofilm inhibition and quorum sensing disruption along with a molecular docking study

S Boudiba, AN Tamfu, K Hanini… - Journal of Chemical …, 2023 - journals.sagepub.com
Molecules that target quorum sensing and biofilm inhibition are useful antimicrobials. In this
regard, a new diarylhydrazone was synthesized and characterized using infrared, high …