This overview on skin delivery considers the evolution of the principles of percutaneous
absorption and skin products from ancient times to today. Over the ages, it has been …

The composition and architecture of the stratum corneum render it a formidable barrier to the
topical and transdermal administration of therapeutic agents. The physicochemical …

Currently, there is no available needle-free approach for diabetics to monitor glucose levels
in the interstitial fluid. Here, we report a path-selective, non-invasive, transdermal glucose …

Overcoming the physiological barriers in the eye remains a key obstacle in the field of ocular
drug delivery. While ocular barriers naturally have a protective function, they also limit drug …

World consumers are nowadays more focused on their health and appearance. This trend is
creating heightened demand for products formulated with natural and nutraceutical …

Transdermal delivery of pharmacologically active agents has been extensively studied for
the past 40 years. Despite the strong efforts, currently, only about 40 products are in market …

Proteins are important biologic therapeutics used for the treatment of various diseases.
However, owing to low bioavailability and poor skin permeability, transdermal delivery of …

The concept of targeted and controlled drug delivery, which directs treatment to precise
anatomical sites, offers benefits such as fewer side effects, reduced toxicity, optimized …

Objective The basic concepts, major mechanisms, technological developments and
advantages of the topical application of lipid-based systems (microemulsions …

Iontophoresis is a technique used to enhance the transdermal delivery of compounds
through the skin via the application of a small electric current. By the process of …