Fluorescent analogs of biomolecular building blocks: design, properties, and applications
Fluorescence spectroscopy, one of the most informative and sensitive analytical techniques,
has played and continues to play key roles in modern research. Indeed, unraveling the inner …
has played and continues to play key roles in modern research. Indeed, unraveling the inner …
Fundamental photophysics of isomorphic and expanded fluorescent nucleoside analogues
Fluorescent nucleoside analogues (FNAs) are structurally diverse mimics of the natural
essentially non-fluorescent nucleosides which have found numerous applications in probing …
essentially non-fluorescent nucleosides which have found numerous applications in probing …
Fluorescent nucleic acid base analogues
LM Wilhelmsson - Quarterly reviews of biophysics, 2010 - cambridge.org
The use of fluorescent nucleic acid base analogues is becoming increasingly important in
the fields of biology, biochemistry and biophysical chemistry as well as in the field of DNA …
the fields of biology, biochemistry and biophysical chemistry as well as in the field of DNA …
Fluorescent DNA base replacements: reporters and sensors for biological systems
We describe the design, synthesis, and properties of nucleoside monomers in which the
DNA base is replaced by fluorescent hydrocarbons and heterocycles, and the assembly of …
DNA base is replaced by fluorescent hydrocarbons and heterocycles, and the assembly of …
Simple fluorescent pyrimidine analogues detect the presence of DNA abasic sites
A family of simple pyrimidine analogues has been synthesized, and their photophysical
properties have been investigated. The most responsive of the family was incorporated in …
properties have been investigated. The most responsive of the family was incorporated in …
Characterization and use of an unprecedentedly bright and structurally non-perturbing fluorescent DNA base analogue
P Sandin, K Börjesson, H Li, J Mårtensson… - Nucleic acids …, 2008 - academic.oup.com
This article presents the first evidence that the DNA base analogue 1, 3-diaza-2-
oxophenoxazine, tC O, is highly fluorescent, both as free nucleoside and incorporated in an …
oxophenoxazine, tC O, is highly fluorescent, both as free nucleoside and incorporated in an …
Fluorescent pyrimidine ribonucleotide: synthesis, enzymatic incorporation, and utilization
SG Srivatsan, Y Tor - Journal of the American Chemical Society, 2007 - ACS Publications
Fluorescent nucleobase analogues that respond to changes in their microenvironment are
valuable for studying RNA structure, dynamics, and recognition. The most commonly used …
valuable for studying RNA structure, dynamics, and recognition. The most commonly used …
Furan decorated nucleoside analogues as fluorescent probes: synthesis, photophysical evaluation, and site-specific incorporation
The synthesis and photophysical evaluation of modified nucleoside analogues in which a
five-membered heterocycle (furan, thiophene, oxazole, and thiazole) is attached to the 5 …
five-membered heterocycle (furan, thiophene, oxazole, and thiazole) is attached to the 5 …
Development and applications of fluorescent oligonucleotides
U Asseline - Current Organic Chemistry, 2006 - ingentaconnect.com
Fluorescent oligonucleotides (FONs) are used in a wide variety of areas such as molecular
and mechanistics biological studies, molecular diagnostics, therapeutic development …
and mechanistics biological studies, molecular diagnostics, therapeutic development …
cycloSal Phosphates as Chemical Trojan Horses for Intracellular Nucleotide and Glycosylmonophosphate Delivery — Chemistry Meets Biology
C Meier - European journal of organic chemistry, 2006 - Wiley Online Library
Pronucleotides represent a promising alternative to improve the biological activity of
nucleoside analogs in antiviral and cancer chemotherapy. In addition, pronucleotides are …
nucleoside analogs in antiviral and cancer chemotherapy. In addition, pronucleotides are …