Fluorescent analogs of biomolecular building blocks: design, properties, and applications

RW Sinkeldam, NJ Greco, Y Tor - Chemical reviews, 2010 - ACS Publications
Fluorescence spectroscopy, one of the most informative and sensitive analytical techniques,
has played and continues to play key roles in modern research. Indeed, unraveling the inner …

Fundamental photophysics of isomorphic and expanded fluorescent nucleoside analogues

D Dziuba, P Didier, S Ciaco, A Barth… - Chemical Society …, 2021 - pubs.rsc.org
Fluorescent nucleoside analogues (FNAs) are structurally diverse mimics of the natural
essentially non-fluorescent nucleosides which have found numerous applications in probing …

Fluorescent nucleic acid base analogues

LM Wilhelmsson - Quarterly reviews of biophysics, 2010 - cambridge.org
The use of fluorescent nucleic acid base analogues is becoming increasingly important in
the fields of biology, biochemistry and biophysical chemistry as well as in the field of DNA …

Fluorescent DNA base replacements: reporters and sensors for biological systems

JN Wilson, ET Kool - Organic & biomolecular chemistry, 2006 - pubs.rsc.org
We describe the design, synthesis, and properties of nucleoside monomers in which the
DNA base is replaced by fluorescent hydrocarbons and heterocycles, and the assembly of …

Simple fluorescent pyrimidine analogues detect the presence of DNA abasic sites

NJ Greco, Y Tor - Journal of the American Chemical Society, 2005 - ACS Publications
A family of simple pyrimidine analogues has been synthesized, and their photophysical
properties have been investigated. The most responsive of the family was incorporated in …

Characterization and use of an unprecedentedly bright and structurally non-perturbing fluorescent DNA base analogue

P Sandin, K Börjesson, H Li, J Mårtensson… - Nucleic acids …, 2008 - academic.oup.com
This article presents the first evidence that the DNA base analogue 1, 3-diaza-2-
oxophenoxazine, tC O, is highly fluorescent, both as free nucleoside and incorporated in an …

Fluorescent pyrimidine ribonucleotide: synthesis, enzymatic incorporation, and utilization

SG Srivatsan, Y Tor - Journal of the American Chemical Society, 2007 - ACS Publications
Fluorescent nucleobase analogues that respond to changes in their microenvironment are
valuable for studying RNA structure, dynamics, and recognition. The most commonly used …

Furan decorated nucleoside analogues as fluorescent probes: synthesis, photophysical evaluation, and site-specific incorporation

NJ Greco, Y Tor - Tetrahedron, 2007 - Elsevier
The synthesis and photophysical evaluation of modified nucleoside analogues in which a
five-membered heterocycle (furan, thiophene, oxazole, and thiazole) is attached to the 5 …

Development and applications of fluorescent oligonucleotides

U Asseline - Current Organic Chemistry, 2006 - ingentaconnect.com
Fluorescent oligonucleotides (FONs) are used in a wide variety of areas such as molecular
and mechanistics biological studies, molecular diagnostics, therapeutic development …

cycloSal Phosphates as Chemical Trojan Horses for Intracellular Nucleotide and Glycosylmonophosphate Delivery — Chemistry Meets Biology

C Meier - European journal of organic chemistry, 2006 - Wiley Online Library
Pronucleotides represent a promising alternative to improve the biological activity of
nucleoside analogs in antiviral and cancer chemotherapy. In addition, pronucleotides are …