Tissue transglutaminase is a multifunctional protein that is likely to play a role in numerous
processes in the nervous system. Tissue transglutaminase posttranslationally modifies …

The transglutaminase (TGase) family of enzymes, of which seven different members are
known in the human genome, participate in many biological processes involving cross …

Tissue transglutaminase (tTG) is a calcium-dependent enzyme that catalyzes the
posttranslational modification of proteins by transamidation of specific polypeptide-bound …

Transglutaminase is a calcium-activated enzyme that crosslinks substrate proteins into
insoluble, often filamentous aggregates resistant to proteases. Because the neurofibrillary …

Extensive protein cross-linking and aggregation are some of the most common molecular
events in the pathogenesis of Alzheimer's disease (AD). Both β-amyloid (Aβ) plaques and …

Tissue transglutaminase is a normal constituent of the central and peripheral nervous
systems and in rats transglutaminase activity in brain and spinal cord is highest during fetal …

Tissue-type transglutaminases (TGases) were recently shown to exert dual enzymatic
activities; they catalyze the posttranslational modification of proteins by transamidation, and …

Skeletal muscle regeneration is triggered by local inflammation and is accompanied by
phagocytosis of dead cells at the injury site. Efferocytosis regulates the inflammatory …

Tissue transglutaminase is a unique member of the transglutaminase family as it not only
catalyzes a transamidating reaction, but also binds and hydrolyzes GTP and ATP. Tissue …

The 30 kDa β‐galactoside‐binding protein of baby hamster kidney (BHK) cells [Mehul et
al.(1994), J. Biol. Chem. 269, 18250–18258] homologous to galectin 3, a widely distributed …