The immunobiology of corneal HSV-1 infection and herpetic stromal keratitis

F Antony, D Kinha, A Nowińska, BT Rouse… - Clinical Microbiology …, 2024 - journals.asm.org
SUMMARY Human alphaherpesvirus 1 (HSV-1) is a highly successful neurotropic pathogen
that primarily infects the epithelial cells lining the orofacial mucosa. After primary lytic …

[HTML][HTML] Herpes simplex keratitis: A brief clinical overview

M Musa, E Enaholo, G Aluyi-Osa… - World Journal of …, 2024 - ncbi.nlm.nih.gov
The aim of our minireview is to provide a brief overview of the diagnosis, clinical aspects,
treatment options, management, and current literature available regarding herpes simplex …

The opportunities and challenges of epigenetic approaches to manage herpes simplex infections

SM Saddoris, LM Schang - Expert Review of Anti-infective Therapy, 2024 - Taylor & Francis
Introduction Despite the existence of antivirals that potently and efficiently inhibit the
replication of herpes simplex virus 1 and 2 (HSV-1,− 2), their ability to establish and …

Harmol used for the treatment of herpes simplex virus induced keratitis

H Xu, N Zhou, Z Huang, J Wu, Y Qian - Virology Journal, 2024 - Springer
Herpes simplex virus type 1 (HSV-1) infection of the eyes results in herpes simplex keratitis
(HSK), which has led to vision loss and even blindness in patients. However, the rate of drug …

Characterization of Research Support of Genome Editing Technologies and Transition to Clinical Trials

R Mohan, SB Haga - The CRISPR Journal, 2024 - liebertpub.com
Genome editing technologies have become widely used research tools. To assess the rate
of growth with respect to federal funding of gene editing projects, we analyzed publicly …

The HUSH-SETDB1-MORC2 epigenetic repressor complex restricts herpesvirus infection in association with PML nuclear bodies

S Roubille, F Juillard, T Escure, O Binda, A Corpet… - 2023 - hal.science
The establishment of latent herpes simplex virus 1 (HSV-1) infection is controlled by
promyelocytic leukemia nuclear bodies (PML NBs). Viral genomes are recruited to PML NBs …

[PDF][PDF] Evaluación de la actividad anti-herpética de sistemas nanoparticulados de riolozatriona

GY Solís Cruz - 2023 - eprints.uanl.mx
Los miembros de la familia Herpesviridae son virus de ADN grandes con un tamaño que va
de los 120 a los 260 nm. El virión de todos los herpesvirus se compone de cuatro …

[PDF][PDF] Ocular Gene Therapy

M Naser, MM Nasr, LH Shehata - 2022 - researchgate.net
This literature offers complete information about the advances in gene treatment in the of the
eye, inclusive of cornea, conjunctiva, lacrimal gland, and trabecular meshwork. We talked …