The use of zebrafish (Danio rerio) as biomedical models
T Teame, Z Zhang, C Ran, H Zhang, Y Yang… - Animal …, 2019 - academic.oup.com
Implications Because of its fully sequenced genome, easy genetic manipulation, high
fecundity, external fertilization and rapid development, and nearly transparent embryo …
fecundity, external fertilization and rapid development, and nearly transparent embryo …
Modeling inflammation in zebrafish for the development of anti-inflammatory drugs
Y Xie, AH Meijer, MJM Schaaf - Frontiers in cell and developmental …, 2021 - frontiersin.org
Dysregulation of the inflammatory response in humans can lead to various inflammatory
diseases, like asthma and rheumatoid arthritis. The innate branch of the immune system …
diseases, like asthma and rheumatoid arthritis. The innate branch of the immune system …
[HTML][HTML] Effects of chronic exposure of naturally weathered microplastics on oxidative stress level, behaviour, and mitochondrial function of adult zebrafish (Danio rerio …
Microplastics (MPs) are a big and growing environmental concern, with studies showing
sublethal to acute biological impacts on typical aquatic organisms. However, little is known …
sublethal to acute biological impacts on typical aquatic organisms. However, little is known …
Nontoxic amphiphilic carbon dots as promising drug nanocarriers across the blood–brain barrier and inhibitors of β-amyloid
The blood–brain barrier (BBB) is a main obstacle for drug delivery targeting the central
nervous system (CNS) and treating Alzheimer's disease (AD). In order to enhance the …
nervous system (CNS) and treating Alzheimer's disease (AD). In order to enhance the …
The African turquoise killifish: A research organism to study vertebrate aging and diapause
The African turquoise killifish has recently gained significant traction as a new research
organism in the aging field. Our understanding of aging has strongly benefited from …
organism in the aging field. Our understanding of aging has strongly benefited from …
Exosomes and biomimetic nanovesicles-mediated anti-glioblastoma therapy: a head-to-head comparison
JY Wu, YJ Li, XB Hu, S Huang, S Luo, T Tang… - Journal of Controlled …, 2021 - Elsevier
Exosomes (Exos) are promising vehicles for brain drug delivery due to nanosize and the
ability to breach the blood–brain barrier (BBB). But the low yield of natural exosomes limits …
ability to breach the blood–brain barrier (BBB). But the low yield of natural exosomes limits …
Enrichment for laboratory zebrafish—A review of the evidence and the challenges
Simple Summary The zebrafish is one of the most commonly used animals in scientific
research, but there remains a lack of consensus over good practice for zebrafish housing …
research, but there remains a lack of consensus over good practice for zebrafish housing …
Assessing fish welfare in research and aquaculture, with a focus on European directives
M Toni, A Manciocco, E Angiulli, E Alleva, C Cioni… - Animal, 2019 - cambridge.org
The number of farmed fish in the world has increased considerably. Aquaculture is a
growing industry that will in the future provide a large portion of fishery products. Moreover …
growing industry that will in the future provide a large portion of fishery products. Moreover …
[HTML][HTML] The short-lived African turquoise killifish: an emerging experimental model for ageing
Human ageing is a fundamental biological process that leads to functional decay, increased
risk for various diseases and, ultimately, death. Some of the basic biological mechanisms …
risk for various diseases and, ultimately, death. Some of the basic biological mechanisms …
Early exposure to environmental levels of sulfamethoxazole triggers immune and inflammatory response of healthy zebrafish larvae
Trace levels of antibiotics are increasingly being detected in aquatic environment and their
potential toxicity to aquatic organisms is concerning. Sulfamethoxazole (SMX), a veterinary …
potential toxicity to aquatic organisms is concerning. Sulfamethoxazole (SMX), a veterinary …