Cinnamic acid derivatives and their biological efficacy
N Ruwizhi, BA Aderibigbe - International journal of molecular sciences, 2020 - mdpi.com
The role played by cinnamic acid derivatives in treating cancer, bacterial infections, diabetes
and neurological disorders, among many, has been reported. Cinnamic acid is obtained …
and neurological disorders, among many, has been reported. Cinnamic acid is obtained …
Biological activity of oxadiazole and thiadiazole derivatives
UA Atmaram, SM Roopan - Applied Microbiology and Biotechnology, 2022 - Springer
The 5-membered oxadiazole and thiadiazole scaffolds are the most privileged and well-
known heterocycles, being a common and essential feature of a variety of natural products …
known heterocycles, being a common and essential feature of a variety of natural products …
Novel 1, 2, 4-oxadiazole derivatives in drug discovery
Five-membered 1, 2, 4-oxadiazole heterocyclic ring has received considerable attention
because of its unique bioisosteric properties and an unusually wide spectrum of biological …
because of its unique bioisosteric properties and an unusually wide spectrum of biological …
[HTML][HTML] A review on synthetic account of 1, 2, 4-oxadiazoles as anti-infective agents
TM Dhameliya, SJ Chudasma, TM Patel, BP Dave - Molecular Diversity, 2022 - Springer
Most of the currently marketed drugs consist of heterocyclic scaffolds containing nitrogen
and or oxygen as heteroatoms in their structures. Several research groups have synthesized …
and or oxygen as heteroatoms in their structures. Several research groups have synthesized …
Coumarin-benzothiazole based azo dyes: synthesis, characterization, computational, photophysical and biological studies
B Manjunatha, YD Bodke, O Nagaraja… - Journal of Molecular …, 2021 - Elsevier
In this paper, we have reported the synthesis of some coumarin-benzothiazole based azo
dyes (C 1-C 5). The structure of the synthesised dyes was precisely established from their …
dyes (C 1-C 5). The structure of the synthesised dyes was precisely established from their …
Recent advancements and developments in search of anti-tuberculosis agents: a quinquennial update and future directions
Tuberculosis (TB) has been considered as the highly chronic, contagious and infectious
disorder caused by Mycobacterium tuberculosis (Mtb). Every year more than 10 million …
disorder caused by Mycobacterium tuberculosis (Mtb). Every year more than 10 million …
A comprehensive review of recent advances in the biological activities of 1, 2, 4‐oxadiazoles
OM Hendawy - Archiv der Pharmazie, 2022 - Wiley Online Library
Nitrogen heterocycles play an essential role in medication development. The 1, 2, 4‐
oxadiazole heterocycle has been extensively studied, yielding a large variety of molecules …
oxadiazole heterocycle has been extensively studied, yielding a large variety of molecules …
In vitro anti-TB properties, in silico target validation, molecular docking and dynamics studies of substituted 1, 2, 4-oxadiazole analogues against Mycobacterium …
The alarming increase in multi-and extensively drug-resistant (MDR and XDR) strains of
Mycobacterium tuberculosis (MTB) has triggered the scientific community to search for …
Mycobacterium tuberculosis (MTB) has triggered the scientific community to search for …
Design, synthesis, anticancer evaluation and molecular docking studies of 1, 2, 4-oxadiazole incorporated indazole-isoxazole derivatives
J Lingam, BK Sahoo, BD Mallavarapu… - Synthetic …, 2024 - Taylor & Francis
Abstract A new series of 1, 2, 4-oxadiazole incorporated indazole-isoxazole (12a–j)
derivatives were designed, synthesized and confirmed their structures by 1HNMR, 13CNMR …
derivatives were designed, synthesized and confirmed their structures by 1HNMR, 13CNMR …
Bioisosterism: 1, 2, 4‐Oxadiazole Rings
M Camci, N Karali - ChemMedChem, 2023 - Wiley Online Library
Although studies in drug discovery have gained momentum in recent years, the conversion
of drugs in use today into less toxic derivatives with pharmacologically superior properties is …
of drugs in use today into less toxic derivatives with pharmacologically superior properties is …