Anticancer activity of glycoalkaloids from Solanum plants: A review

MJ Winkiel, S Chowański, M Słocińska - Frontiers in Pharmacology, 2022 - frontiersin.org
Cancer is still one of the main causes of death worldwide. For this reason, new compounds
that have chemotherapeutic potential have been identified. One such group of substances is …

The emerging role of noncoding RNAs in the EGFR signaling pathway in lung cancer

S Mohan, MA Hakami, HG Dailah, A Khalid… - … -Research and Practice, 2023 - Elsevier
Noncoding ribonucleic acids (ncRNAs) have surfaced as essential orchestrators within the
intricate system of neoplastic biology. Specifically, the epidermal growth factor receptor …

Antitumoral activity of Caralluma europaea on colorectal and prostate cancer cell lines

I Samiry, A Pinon, Y Limami, S Rais, Y Zaid… - Journal of Toxicology …, 2023 - Taylor & Francis
Caralluma europaea is a medicinal plant used in Moroccan popular medicine, which has
been employed as a remedy attributed to its anti-inflammatory, antipyretic, antinociceptive …

Rational design of solid lipid-polymer hybrid nanoparticles: An innovative glycoalkaloids-carrier with potential for topical melanoma treatment

YG Gonçalves, M Kravicz, TNC Massaro… - Colloids and Surfaces B …, 2024 - Elsevier
Despite the promising potential of Solanum plant glycoalkaloids in combating skin cancer,
their clinical trials have been halted due to dose-dependent toxicity and poor water …

Health Benefits of the Alkaloids from Lobeira (Solanum lycocarpum St. Hill): A Comprehensive Review

FT Borsoi, GM Pastore, HS Arruda - Plants, 2024 - mdpi.com
Solanum is the largest genus within the Solanaceae family and has garnered considerable
attention in chemical and biological investigations over the past 30 years. In this context …

Evaluation of in vivo and in vitro efficacy of solasonine/solamargine-loaded lipid-polymer hybrid nanoparticles against bladder cancer

IPS Carvalho, LB Silva, RLF do Amaral… - International Journal of …, 2024 - Elsevier
Solasonine (SS) and solamargine (SM) are alkaloids known for their antioxidant and
anticancer properties, which can be further enhanced by encapsulating them in …

Stability, release, and tyrosinase inhibition behaviors of kojic acid encapsulated in the interlayer space of layered yttrium hydroxide

M Kang, Y Choi, SH Byeon - Applied Clay Science, 2024 - Elsevier
Kojic acid (KA) is widely utilized in cosmetic formulations for skin brightening and as a food
preservative to prevent oxidative browning in fruits and vegetables. However, its …

Suppression of melanoma growth in a murine tumour model using orthosiphon stamineus benth. Extract loaded in ethanolic phospholipid vesicles (spherosome)

VM Nazari, S Mahmood, AM Shah… - Current Drug …, 2022 - ingentaconnect.com
Background: Orthosiphon stamineus Benth (OS) is a traditional south-east Asian herb. The
extract of OS is used in the formulation of ethanolic nanolipid vesicle system to have …

Liposome preparation of alpha-arbutin: stability and toxicity assessment using mouse B16F10 melanoma cells

AR Viana, TC Poleze, F da S Bruckmann… - Journal of Toxicology …, 2024 - Taylor & Francis
Melanoma is the most aggressive type of skin cancer, with few therapeutic alternatives
following metastasis development. In recent years, drug delivery-associated …

Main chemical constituents and mechanism of anti‐tumor action of Solanum nigrum L

Z Zhao, C Hu, L Li, J Zhang, L Zhang - Cancer Medicine, 2024 - Wiley Online Library
Abstract Objective Solanum nigrum L.(SNL) is a natural drugwith diverse bioactive
components and multi‐targeted anti‐tumor effects, gaining increasing attention in clinical …