Anticancer activity of glycoalkaloids from Solanum plants: A review
MJ Winkiel, S Chowański, M Słocińska - Frontiers in Pharmacology, 2022 - frontiersin.org
Cancer is still one of the main causes of death worldwide. For this reason, new compounds
that have chemotherapeutic potential have been identified. One such group of substances is …
that have chemotherapeutic potential have been identified. One such group of substances is …
The emerging role of noncoding RNAs in the EGFR signaling pathway in lung cancer
Noncoding ribonucleic acids (ncRNAs) have surfaced as essential orchestrators within the
intricate system of neoplastic biology. Specifically, the epidermal growth factor receptor …
intricate system of neoplastic biology. Specifically, the epidermal growth factor receptor …
Antitumoral activity of Caralluma europaea on colorectal and prostate cancer cell lines
Caralluma europaea is a medicinal plant used in Moroccan popular medicine, which has
been employed as a remedy attributed to its anti-inflammatory, antipyretic, antinociceptive …
been employed as a remedy attributed to its anti-inflammatory, antipyretic, antinociceptive …
Rational design of solid lipid-polymer hybrid nanoparticles: An innovative glycoalkaloids-carrier with potential for topical melanoma treatment
YG Gonçalves, M Kravicz, TNC Massaro… - Colloids and Surfaces B …, 2024 - Elsevier
Despite the promising potential of Solanum plant glycoalkaloids in combating skin cancer,
their clinical trials have been halted due to dose-dependent toxicity and poor water …
their clinical trials have been halted due to dose-dependent toxicity and poor water …
Health Benefits of the Alkaloids from Lobeira (Solanum lycocarpum St. Hill): A Comprehensive Review
Solanum is the largest genus within the Solanaceae family and has garnered considerable
attention in chemical and biological investigations over the past 30 years. In this context …
attention in chemical and biological investigations over the past 30 years. In this context …
Evaluation of in vivo and in vitro efficacy of solasonine/solamargine-loaded lipid-polymer hybrid nanoparticles against bladder cancer
IPS Carvalho, LB Silva, RLF do Amaral… - International Journal of …, 2024 - Elsevier
Solasonine (SS) and solamargine (SM) are alkaloids known for their antioxidant and
anticancer properties, which can be further enhanced by encapsulating them in …
anticancer properties, which can be further enhanced by encapsulating them in …
Stability, release, and tyrosinase inhibition behaviors of kojic acid encapsulated in the interlayer space of layered yttrium hydroxide
M Kang, Y Choi, SH Byeon - Applied Clay Science, 2024 - Elsevier
Kojic acid (KA) is widely utilized in cosmetic formulations for skin brightening and as a food
preservative to prevent oxidative browning in fruits and vegetables. However, its …
preservative to prevent oxidative browning in fruits and vegetables. However, its …
Suppression of melanoma growth in a murine tumour model using orthosiphon stamineus benth. Extract loaded in ethanolic phospholipid vesicles (spherosome)
Background: Orthosiphon stamineus Benth (OS) is a traditional south-east Asian herb. The
extract of OS is used in the formulation of ethanolic nanolipid vesicle system to have …
extract of OS is used in the formulation of ethanolic nanolipid vesicle system to have …
Liposome preparation of alpha-arbutin: stability and toxicity assessment using mouse B16F10 melanoma cells
AR Viana, TC Poleze, F da S Bruckmann… - Journal of Toxicology …, 2024 - Taylor & Francis
Melanoma is the most aggressive type of skin cancer, with few therapeutic alternatives
following metastasis development. In recent years, drug delivery-associated …
following metastasis development. In recent years, drug delivery-associated …
Main chemical constituents and mechanism of anti‐tumor action of Solanum nigrum L
Z Zhao, C Hu, L Li, J Zhang, L Zhang - Cancer Medicine, 2024 - Wiley Online Library
Abstract Objective Solanum nigrum L.(SNL) is a natural drugwith diverse bioactive
components and multi‐targeted anti‐tumor effects, gaining increasing attention in clinical …
components and multi‐targeted anti‐tumor effects, gaining increasing attention in clinical …