Nuclear medicine imaging in neuroblastoma: current status and new developments

A Samim, GAM Tytgat, G Bleeker, STM Wenker… - Journal of Personalized …, 2021 - mdpi.com
Neuroblastoma is the most common extracranial solid malignancy in children. At diagnosis,
approximately 50% of patients present with metastatic disease. These patients are at high …

Norepinephrine transporter as a target for imaging and therapy

N Pandit-Taskar, S Modak - Journal of Nuclear Medicine, 2017 - Soc Nuclear Med
The norepinephrine transporter (NET) is essential for norepinephrine uptake at the synaptic
terminals and adrenal chromaffin cells. In neuroendocrine tumors, NET can be targeted for …

Guidelines on nuclear medicine imaging in neuroblastoma

Z Bar-Sever, L Biassoni, B Shulkin, G Kong… - European journal of …, 2018 - Springer
Nuclear medicine has a central role in the diagnosis, staging, response assessment and
long-term follow-up of neuroblastoma, the most common solid extracranial tumour in …

Diagnosis, treatment response, and prognosis: the role of 18F-DOPA PET/CT in children affected by neuroblastoma in comparison with 123I-mIBG scan: the first …

A Piccardo, G Morana, M Puntoni… - Journal of Nuclear …, 2020 - Soc Nuclear Med
Our purpose was to evaluate the diagnostic role of 18F-3, 4-dihydroxyphenylalanine (DOPA)
PET/CT at the time of staging in children with neuroblastoma and to investigate its ability to …

Risk stratification of pediatric patients with neuroblastoma using volumetric parameters of 18F-FDG and 18F-DOPA PET/CT

CJ Liu, MY Lu, YL Liu, CL Ko, KY Ko… - Clinical Nuclear …, 2017 - journals.lww.com
Purpose This study determined the prognostic value of volumetric parameters derived from
pretreatment 18 F-FDG and 18 F-DOPA PET/CT of neuroblastoma and their correlation with …

[177Lu]Lu-DOTA-TATE and [131I]MIBG Phenotypic Imaging-Based Therapy in Metastatic/Inoperable Pheochromocytomas and Paragangliomas: Comparative …

S Prado-Wohlwend, MI del Olmo-García… - Frontiers in …, 2022 - frontiersin.org
Purpose The aim of the study is to assess phenotypic imaging patterns and the response to
treatment with [177Lu] Lu-DOTA-TATE and/or [131I] MIBG in paragangliomas (PGLs) and …

Prognostic value of interim 18F-DOPA and 18F-FDG PET/CT findings in stage 3–4 pediatric neuroblastoma

KY Ko, RF Yen, CL Ko, SW Chou… - Clinical Nuclear …, 2022 - journals.lww.com
Purpose This retrospective study aimed to determine the prognostic value of imaging
parameters derived from midtherapy 18 F-fluorodihydroxyphenylalanine (18 F-DOPA) and …

Neuroblastoma: MIBG imaging and new tracers

T Pfluger, A Piccardo - Seminars in Nuclear Medicine, 2017 - Elsevier
Neuroblastoma is an embryonic tumor of the peripheral sympathetic nervous system, and is
metastatic or otherwise high risk for relapse in nearly 50% of cases, with a long-term survival …

Prognostic value of texture analysis of the primary tumour in high‐risk neuroblastoma: An 18F‐DOPA PET study

F Fiz, G Bottoni, F Bini, F Cerroni… - Pediatric Blood & …, 2022 - Wiley Online Library
Purpose To evaluate the prognostic value of texture analysis of the primary tumour with
18fluorine‐dihydroxyphenylalanine positron emission tomography/X‐ray computed …

Paediatric nuclear medicine imaging

L Biassoni, M Easty - British Medical Bulletin, 2017 - academic.oup.com
Background Nuclear medicine imaging explores tissue viability and function by using
radiotracers that are taken up at cellular level with different mechanism. This imaging …