Synapse organizing proteins are multifaceted molecules that coordinate the complex
processes of brain development and plasticity at the level of individual synapses. Their …

The worldwide prevalence of ASD is around 1%. Although the pathogenesis of ASD is not
entirely understood, it is recognized that a combination of genetic, epigenetics …

A tripartite synapse comprises a neuronal presynaptic axon and a postsynaptic dendrite,
which are closely ensheathed by a perisynaptic astrocyte process. Through their structural …

The establishment of a functional cerebral cortex depends on the proper execution of
multiple developmental steps, culminating in dendritic and axonal outgrowth and the …

The stochastic expression of fewer than 60 clustered protocadherin (cPcdh) isoforms
provides diverse identities to individual vertebrate neurons and a molecular basis for self …

Synapses are specialized intercellular junctions connecting pre-and postsynaptic neurons
into functional neural circuits. Synaptic cell adhesion molecules (CAMs) constitute key …

The family of∼ 60 clustered protocadherins (Pcdhs) are cell adhesion molecules encoded
by a genomic locus that regulates expression of distinct combinations of isoforms in …

Astrocytes are multifaceted glial cell types that perform structural, functional, metabolic, and
homeostatic roles in the brain. Recent studies have revealed mechanisms underlying the …

Alternative splicing in the 3′ UTR of mammalian genes plays a crucial role in diverse
biological processes, including cell differentiation and development. SAM68 is a key splicing …

Clustered protocadherin (Pcdh), a cell adhesion protein, is involved in the self-recognition
and non-self-discrimination of neurons by conferring diversity on the cell surface. Although …