Abstract Ischemia-reperfusion (I/R) injury paradoxically occurs during reperfusion following
ischemia, exacerbating the initial tissue damage. The limited understanding of the intricate …

The involvement of cardiovascular disease in cancer onset and development represents a
contemporary interest in basic science. It has been recognized, from the most recent …

Current sprayable hydrogel masks lack the stepwise protection, cleansing, and nourishment
of extensive wounds, leading to delayed healing with scarring. Here, we develop a …

Obesity increases the risk for cardiovascular diseases and induces cardiomyopathy. Chronic
inflammation plays a significant role in obesity-induced cardiomyopathy and may provide …

Neurodegenerative diseases (NDDs) pose an increasingly prevalent threat to the well-being
and survival of elderly individuals worldwide. NDDs include Alzheimer's disease (AD) …

The Wnt signal transduction pathway has essential roles in the formation of the primary body
axis during development, cellular differentiation and tissue homeostasis. This animal …

BACKGROUND: Cardiac fibroblasts have crucial roles in the heart. In particular, fibroblasts
differentiate into myofibroblasts in the damaged myocardium, contributing to scar formation …

The WNT/β‐catenin pathway is a master regulator of cardiac development and growth, and
its activity is low in healthy adult hearts. However, even this low activity is essential for …

Abstract Circular RNAs (CircRNAs) are a class of regulatory RNA transcripts, which are
ubiquitously expressed in eukaryotes. CircRNA dysregulation has been shown to disrupt the …

Background: The ability of the right ventricle (RV) to adapt to an increased pressure
afterload determines survival in patients with pulmonary arterial hypertension. At present …